Device and method for delivering or withdrawing a substance through the skin

• US 20090112181A1
• Filed: 12/22/2008
• Published: 04/30/2009
• Est. Priority Date: 02/04/2002
• Status: Abandoned Application

• Current Assignee: Alexander G. Lastovich, Diane Sutter, Frank E. Martin, Haider M. Ishaq, James K. Fentress, Julia Griggs, Ronald J. Pettis
• Original Assignee: Alexander G. Lastovich, Diane Sutter, Frank E. Martin, Haider M. Ishaq, James K. Fentress, Julia Griggs, Ronald J. Pettis
• Inventors: Martin, Frank E., Pettis, Ronald J., Haider, M. Ishaq, Lastovich, Alexander G., Fentress, James K., Griggs, Julia, Sutter, Diane
• Application Number:
  US12/341,589
• Publication Number:
  US 20090112181A1
• Time in Patent Office: Days
• US Class Current: 604/506
• CPC Class Codes: A61M 37/0015 by using microneedles
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/3007 with specially designed jet passages at the injector's distal end
• CPC Class Codes: A61M 5/425 Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion

Abstract

An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. A device includes a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid.

Claims

1. A method of delivering a substance through at least one layer of the skin of a subject, the method comprising the steps of:

providing a device having a substantially circular shaped body having a top face, a bottom face spaced from the top face, and a side edge having a flange, the body having a channel, wherein the bottom face includes at least one raised conical frustum shaped protrusion disposed on the bottom face having a skin abutment surface;

at least one dermal-access member being provided in each of the at least one raised conical frustum shaped protrusion and in fluid communication with the channel, wherein the at least one dermal-access member extends from about 0.3 mm to about 3 mm from the skin abutment surface wherein the channel is fluidically coupled to a fluid delivery system selected from the group consisting of syringe, pump, and medication delivery pen;

positioning the at least one dermal-access member on a target site of the skin of the subject;

applying a pressure against the device sufficient for the at least one dermal-access member to penetrate the skin and for the skin abutment surface to contact the skin; and

delivering a substance to the target site of the subject.

2. The method of claim 1, further comprising adhesively attaching the device to the skin of the subject.

3. The method of claim 1, wherein the dermal-access member penetrates the skin at a targeted depth.

4. The method of claim 1, wherein the substance is delivered to an intradermal layer of the skin.

5. The method of claim 1, wherein the at least one dermal-access member is a needle.