FLUID ANALYTICAL DEVICE

• US 20090114608A1
• Filed: 04/01/2008
• Published: 05/07/2009
• Est. Priority Date: 11/02/2007
• Status: Active Grant

• Current Assignee: Industrial Technology Research Institute
• Original Assignee: Industrial Technology Research Institute
• Inventors: Tsai, Chung-Hsien, Hsieh, Wen-Pin, Chung, Cheng-Shiu
• Granted Patent: US 8,002,995 B2
• Time in Patent Office: Days
• US Class Current: 210/789
• CPC Class Codes: G01N 33/491 by separating the blood components G01N15/05 takes precedence

Abstract

A fluid analytical device is provided comprising a body, a reservoir, an inlet channel and a separation unit. The reservoir is formed on the body. The inlet channel is formed on the body connected to the reservoir. The separation unit is formed on the body connected to the inlet channel, which comprises a pile area, a collecting area and a spacer. The collecting area is located between the pile area and the reservoir. The spacer is formed between the pile area and the collecting area.

Claims

1. A fluid analytical device, comprising:

a body;

a reservoir, formed on the body;

an inlet channel, formed on the body connected to the reservoir; and

a separation unit, formed on the body connected to the inlet channel, comprising;

a pile area;

a collecting area, located between the pile area and the reservoir; and

a spacer, formed between the pile area and the collecting area.

2. The fluid analytical device as claimed in claim 1, wherein a volume of the collecting area is smaller than a volume of the pile area.

3. The fluid analytical device as claimed in claim 1, wherein a volume ratio between the pile area and the collecting area is between 1:

1 and 2;

1.

4. The fluid analytical device as claimed in claim 1, wherein a ratio between a depth of the spacer and a depth of the collecting area is about between ⅓

and ⅙

.

5. The fluid analytical device as claimed in claim 1, wherein the inlet channel connects the separation unit in a location above the spacer.

6. The fluid analytical device as claimed in claim 1, wherein the body is circular, and a width of the pile area along a periphery direction is greater than a width of the collecting area along the periphery direction.

7. The fluid analytical device as claimed in claim 1, further comprising a exhaust channel connecting the collecting area and the reservoir.

8. The fluid analytical device as claimed in claim 1, wherein the reservoir comprises a spiral groove formed on a bottom thereof.

9. The fluid analytical device as claimed in claim 1, wherein the spacer further comprises a plurality of guiding grooves formed on a top thereof.

10. The fluid analytical device as claimed in claim 1, wherein when the fluid analytical device separates a fluid, a first fluid constituent is moved to the pile area, and a second fluid constituent is moved to the collecting area due to specific weight difference therebetween.

11. The fluid analytical device as claimed in claim 1, wherein the fluid is blood, the first fluid constituent is blood cells, and the second fluid constituent is plasma.

12. A fluid analytical method for separating a first fluid constituent and a second fluid constituent, comprising:

providing the fluid analytical device as claimed in claim 1; and

rotating the fluid analytical device to separate the first and second fluid constituents, wherein the fluid analytical device is rotated with respect to the reservoir.

13. A fluid analytical device, comprising:

a first body, comprising a spiral groove and a first drain, wherein the first drain is connected to a bottom of the spiral groove passing through the first body;

a second body, comprising;

a first separation room, connected to the first drain;

a second drain, connected to the first separation room, wherein the second drain is ring shaped;

a second separation room; and

a capillary, connecting the second separation room and the second drain.

14. The fluid analytical device as claimed in claim 13, wherein the first body further comprises a first exhaust groove, connecting an upper portion of the spiral groove and the first separation room.

15. The fluid analytical device as claimed in claim 13, wherein the first body further comprises a second exhaust groove connected to the second separation room.

16. The fluid analytical device as claimed in claim 13, wherein the second body further comprises a waste liquid room connected to the second drain.

17. The fluid analytical device as claimed in claim 16, wherein the first body further comprises a third exhaust groove connected to the waste liquid room.

18. A fluid analytical method for separating a first fluid constituent and a second fluid constituent, comprising:

providing the fluid analytical device as claimed in claim 13;

infusing the fluid into the spiral groove;

rotating the fluid analytical device in a first direction, wherein the fluid enters the first separation room, and the first fluid constituent is separated from the second fluid constituent; and

rotating the fluid analytical device in a second direction, wherein the second fluid constituent flows from the first separation room, passing the second drain and the capillary, and enters the second separation room.

19. The fluid analytical method as claimed in claim 18, wherein the fluid is blood, the first fluid constituent is blood cells, and the second fluid constituent is plasma.

20. A fluid analytical method for separating a first fluid constituent and a second fluid constituent, comprising:

providing the fluid analytical device as claimed in claim 13;

infusing the fluid into the spiral groove;

rotating the fluid analytical device in a first speed, wherein the fluid enters the first separation room, and the first fluid constituent is separated from the second fluid constituent; and

rotating the fluid analytical device in a second speed, wherein the second fluid constituent flows from the first separation room, passing the second drain and the capillary, and enters the second separation room.

21. The fluid analytical method as claimed in claim 20, wherein the fluid is blood, the first fluid constituent is blood cells, and the second fluid constituent is plasma.

22. A fluid analytical device, comprising:

a body;

a reservoir, formed on the body;

a plurality of inlet channels, formed on the body connected to the reservoir;

and

a plurality of separation units, formed on the body surrounding the reservoir, wherein each of the separation unit is connected to the inlet channel, and comprises;

a pile area;

a collecting area, located between the pile area and the reservoir; and

a spacer, formed between the pile area and the collecting area.

23. The fluid analytical device as claimed in claim 22, wherein the separation units are arranged equidistantly.

24. A fluid analytical method for separating a first fluid constituent and a second fluid constituent, comprising:

providing the fluid analytical device as claimed in claim 22; and

rotating the fluid analytical device to separate the first and second fluid constituents, wherein the fluid analytical device is rotated with respect to the reservoir.