Microneedle array patch
First Claim
1. A delivery device for introducing a substance into or below the stratum corneum of a patient, comprisinga microneedle having a distal end and an interior channel that extends to the distal end,a pin dimensioned for slidably extending into the interior channel and out the distal end, and an adhesive patch of the type capable of adhering to biological tissue.
4 Assignments
0 Petitions
Accused Products
Abstract
Microneedle devices for transport of molecules, including drugs and biological molecules, across tissue, are provided. The microneedle devices permit drug delivery or removal of body fluids at clinically relevant rates across skin or other tissue barriers, with minimal or no damage, pain, or irritation to the tissue. Microneedles can be formed of biodegradable or non-biodegradable polymeric materials or metals. In a preferred embodiment, a microneedle device includes a plugging element comprising a platform including a plurality of microneedle plugs for preventing skin or other tissue barriers from entering the hollow microneedles. In another preferred embodiment, a microneedle device includes a plurality of bioerodible elements for temporarily plugging the hollow microneedles, thereby preventing skin or other tissue barriers from entering the hollow microneedles.
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Citations
20 Claims
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1. A delivery device for introducing a substance into or below the stratum corneum of a patient, comprising
a microneedle having a distal end and an interior channel that extends to the distal end, a pin dimensioned for slidably extending into the interior channel and out the distal end, and an adhesive patch of the type capable of adhering to biological tissue.
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16. A transdermal patch, comprising at least one microneedle having an interior channel,
a removable plug disposed at a distal end of the interior channel, as an adhesive patch for adhering at least one microneedle to biological tissue.
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17. A method for introducing a substance into or below the stratum corneum of a patient, comprising
inserting into tissue of a patient a microneedle having a distal end and an interior channel that extends to the distal end, and sliding a pin dimensioned into the interior channel and out the distal end.
Specification