Non-invasive analysis and controlled dosage transdermal active patch
First Claim
1. A transdermal patch for programmed delivery of a bio-active agent into the skin of a living body which patch is fastenable to a surface of the skin, the patch containing at least one agent storage pad positioned to dispense agent into the skin and containing electrically operated driver means for causing delivery of the stored agent from the storage pad into the skin and containing a battery for supplying electrical current to skin contact electrodes of the driver means, further including:
- a programmable digital data processor controlling dispensing of said agent by said reservoir pad and driver means;
said data processor programmed to deliver repetitive doses of said agent at a repetition rate which corresponds to the rate at which the concentration of said agent in the body diminishes to a particular value.
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Accused Products
Abstract
A programmable transdermal patch non-invasively delivers pharmaceuticals or other bio-active agents through the skin of a living body. The patch contains one or more agent storage pads and one or more active drivers that apply an electric current to the skin or produce ultrasound to drive the agent into the skin. A digital data processor controls the drivers to match administration of the agents to the needs of the body. The patch may contain a sensor, coupled to the data processor, for monitoring the concentration of a substance in the body in order to vary dosage of a therapeutic agent. A radio contained in the patch enables control by medical personnel from a remote location and/or transmission of sensor data to the remote location. The pads, drivers, sensor, data processor, radio and a battery are all contained within a unitary patch and need no physical connection to external devices.
46 Citations
10 Claims
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1. A transdermal patch for programmed delivery of a bio-active agent into the skin of a living body which patch is fastenable to a surface of the skin, the patch containing at least one agent storage pad positioned to dispense agent into the skin and containing electrically operated driver means for causing delivery of the stored agent from the storage pad into the skin and containing a battery for supplying electrical current to skin contact electrodes of the driver means, further including:
- a programmable digital data processor controlling dispensing of said agent by said reservoir pad and driver means;
said data processor programmed to deliver repetitive doses of said agent at a repetition rate which corresponds to the rate at which the concentration of said agent in the body diminishes to a particular value. - View Dependent Claims (2, 3, 4, 5)
- a programmable digital data processor controlling dispensing of said agent by said reservoir pad and driver means;
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6. A transdermal patch for programmed delivery of a bio-active agent into the skin of a living body which patch is fastenable to a surface of the skin, the patch containing at least one agent storage pad positioned to dispense agent into the skin and containing electrically operated driver means for causing delivery of the stored agent from the storage pad into the skin and containing a battery for supplying electrical current to skin contact electrodes of the driver means, further including:
- a programmable digital data processor controlling dispensing of said agent by said reservoir pad and driver means;
said data processor being programmed to vary the dosage of said agent during a period of time to conform to variations of the rate at which the agent is needed by the body during the period of time. - View Dependent Claims (7, 8, 9, 10)
- a programmable digital data processor controlling dispensing of said agent by said reservoir pad and driver means;
Specification