Pulsatile cochlear implant stimulation strategy

• US 20090125082A1
• Filed: 11/10/2008
• Published: 05/14/2009
• Est. Priority Date: 11/09/2007
• Status: Active Grant

• Current Assignee: MED-EL Elektromedizinische Gerate GmbH (MED-EL Corporation)
• Original Assignee: MED-EL Elektromedizinische Gerate GmbH (MED-EL Corporation)
• Inventors: Schleich, Peter
• Granted Patent: US 8,417,348 B2
• Time in Patent Office: Days
• US Class Current: 607/57
• CPC Class Codes: A61N 1/36038 Cochlear stimulation

Abstract

An implantable device includes a multi-channel electrode array in which each channel is associated with an electrode in the array. An audio processing stage processes an input audio signal to produce output channel signals representing associated bands of audio frequencies. A timing and envelope detector processes the output channel signals in a sequence of sampling intervals, including, for each sampling interval, determining for each output channel signal: i. a set of requested pulse timings containing a plurality of pulse timing requests, and ii. a set of corresponding envelope signals representing pulse magnitude for pulse timing requests. A pulse selection amplitude definition stage determines for each set of requested pulse timings: i. a set of output pulses at specified times selected from the set of requested pulse timings based on a pulse selection inhibition function, and ii. a stimulation amplitude associated with each output pulse. The multi-channel electrode array applies the output pulses at their associated stimulation amplitudes to surrounding tissue.

Claims

1. A method of activating electrodes in an implanted multi-channel electrode array where each channel is associated with an electrode in the array, the method comprising:

processing an input audio signal to produce a plurality of output channel signals each representing an associated band of audio frequencies;

processing the output channel signals in a sequence of sampling intervals, wherein for each sampling interval, the processing includes;

i. determining for each output channel signal;

a) a set of requested pulse timings containing a plurality of pulse timing requests, and

b) a set of corresponding envelope signals representing pulse magnitude for pulse timing requests; and

ii. determining for each set of requested pulse timings;

a) a set of output pulses at specified times selected from the set of requested pulse timings based on a pulse selection inhibition function, and

b) a stimulation amplitude associated with each output pulse; and

activating electrodes in the array with corresponding output pulses at their associated stimulation amplitudes.

2. A method according to claim 1, wherein the inhibition function is constant at times so as to define an absolute inhibition state.

3. A method according to claim 1, wherein the inhibition function is changing at times so as to define a relative inhibition state.

4. A method according to claim 1, wherein the inhibition function is pulse magnitude dependent.

5. A method according to claim 4, wherein the inhibition function reflects a ratio of inhibition state to pulse magnitude.

6. A method according to claim 1, wherein the inhibition function is output channel dependent.

7. A method according to claim 1, wherein output pulses are selected based on length of an inhibition state defined by the inhibition function.

8. A method according to claim 7, wherein output pulses are selected preferentially based on shortness of the inhibition state.

9. A method according to claim 1, wherein the input audio signal includes temporal structure characteristics which are represented in the output channel signals by channel specific sampling sequences (CSSS).

10. A method according to claim 1, wherein the input audio signal includes temporal structure characteristics which are reflected in the specified times of the output pulses.

11. A method according to claim 1, wherein the electrode array is a cochlear implant electrode array.

12. An implantable device having a multi-channel electrode array, each output channel being associated with an electrode in the array, the device comprising:

an audio processing stage for processing an input audio signal to produce a plurality of output channel signals each representing an associated band of audio frequencies;

a timing and envelope detector for processing the output channel signals in a sequence of sampling intervals, wherein for each sampling interval, the processing includes determining for each output channel signal;

i. a set of requested pulse timings containing a plurality of pulse timing requests, and

ii. a set of corresponding envelope signals representing pulse magnitude for pulse timing requests;

a pulse selection amplitude definition stage for determining for each set of requested pulse timings;

i. a set of output pulses at specified times selected from the set of requested pulse timings based on a pulse selection inhibition function, and

ii. a stimulation amplitude associated with each output pulse; and

the multi-channel electrode array for applying the output pulses at their associated stimulation amplitudes to surrounding tissue.

13. An implantable device according to claim 12, wherein the inhibition function is constant at times so as to define an absolute inhibition state.

14. An implantable device according to claim 12, wherein the inhibition function is changing at times so as to define a relative inhibition state.

15. An implantable device according to claim 12, wherein the inhibition function is pulse magnitude dependent.

16. An implantable device according to claim 15, wherein the inhibition function reflects a ratio of inhibition state to pulse magnitude.

17. An implantable device according to claim 12, wherein the inhibition function is output channel dependent.

18. An implantable device according to claim 12, wherein output pulses are selected based on length of an inhibition state defined by the inhibition function.

19. An implantable device according to claim 18, wherein output pulses are selected preferentially based on shortness of the inhibition state.

20. An implantable device according to claim 12, wherein the input audio signal includes temporal structure characteristics which are represented in the output channel signals by channel specific sampling sequences (CSSS).

21. An implantable device according to claim 12, wherein the input audio signal includes temporal structure characteristics which are reflected in the specified times of the output pulses.

22. An implantable device according to claim 12, wherein the electrode array is a cochlear implant electrode array.