AORTIC VALVE STENT GRAFT

• US 20090125098A1
• Filed: 11/04/2008
• Published: 05/14/2009
• Est. Priority Date: 11/09/2007
• Status: Active Grant

• Current Assignee: Cook Medical Incorporated (Cook Group Incorporated)
• Original Assignee: Cook Incorporated (Cook Group Incorporated)
• Inventors: CHUTER, TIMOTHY AM
• Granted Patent: US 8,715,337 B2
• Time in Patent Office: Days
• US Class Current: 623/1.260
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/0007 for adjusting length
• CPC Class Codes: A61F 2250/0048 differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
• CPC Class Codes: A61F 2250/006 modular

Abstract

An implantable endoluminal prosthesis for replacing a damaged aortic valve is provided. In one embodiment, the prosthesis includes a balloon-expandable stent, a tubular conduit that extends into the ascending aorta, and a self-expanding stent. The tubular conduit extends across the balloon-expandable stent. The tubular conduit includes an artificial valve. The self-expanding stent extends across the tubular conduit into the ascending aorta. The balloon-expandable stent, the tubular conduit, and the self-expanding stent are coupled to provide unidirectional flow of fluid into the aorta and further into the coronary arteries. Also provided is a method for implanting the endoluminal prosthesis.

Claims

1. An endoluminal prosthesis comprising:

a first stent;

a tubular conduit comprising an aortic valve replacement, wherein at least a portion of the tubular conduit overlaps at least a portion of the first stent; and

a second stent that overlaps at least a portion of the tubular conduit,

wherein ones of the first stent, the tubular conduit, and the second stent are coaxially arranged for unidirectionally passing fluid through the prosthesis.

2. The endoluminal prosthesis of claim 1, wherein the first stent comprises a balloon-expandable stent and the second stent comprises a self-expanding stent.

3. The endoluminal prosthesis of claim 2, wherein the self-expanding stent at least partially surrounds the tubular conduit, and the tubular conduit at least partially surrounds the balloon-expandable stent.

4. The endoluminal prosthesis of claim 2, wherein both the balloon-expandable stent and the self-expanding stent at least partially surround the tubular conduit.

5. The endoluminal prosthesis of claim 1, wherein the aortic valve replacement comprises an artificial valve.

6. The endoluminal prosthesis of claim 1, wherein the aortic valve replacement is located at the distal end of the tubular conduit.

7. The endoluminal prosthesis of claim 1 further comprising one or more barbs.

8. The endoluminal prosthesis of claim 1, wherein at least one of the first stent or the second stent comprises a braided bottle stent.

9. A prosthesis for replacing an aortic valve comprising:

at least first, second and third tubular members,

wherein one of the first, second or third tubular members comprises a valve, and

wherein ones of the first tubular member, the second tubular member, and the third tubular member are coaxially arranged for unidirectionally passing fluid through the prosthesis.

10. The prosthesis of claim 9, wherein at least one of the first, second and third tubular members comprises a balloon-expandable stent.

11. The prosthesis of claim 9, wherein at least one of the first, second and third tubular members comprises a braided bottle stent.

12. The prosthesis of claim 9, wherein at least one of the first, second and third tubular members comprises a self-expanding stent.

13. The prosthesis of claim 9, wherein the second tubular member comprises a tubular conduit, wherein the valve is located at a distal end of the tubular conduit.

14. The prosthesis of claim 9 further comprising one or more barbs.

15. A method of replacing an aortic valve in a subject, the method comprising:

introducing into a vascular system an endoluminal prosthesis comprising a first stent, a tubular conduit comprising a valve, and a second stent, wherein at least a portion of the tubular conduit overlaps at least a portion of the first stent, and at least a portion of the tubular conduit overlaps at least a portion of the second stent;

advancing the endoluminal prosthesis within the vascular system towards an aortic annulus; and

expanding at least a portion of the prosthesis into engagement with the aortic annulus.

16. The method of claim 15 wherein the first stent comprises a balloon expandable stent and the second stent comprises a self-expanding stent, the method further comprising introducing the balloon expandable stent, the tubular conduit, and the self-expanding stent into the vascular system in a sequential manner.

17. The method of claim 15 wherein the first stent comprises a balloon expandable stent and the second stent comprises a self-expanding stent, the method further comprising introducing the balloon expandable stent, the tubular conduit, and the self-expanding stent into the vascular system simultaneously.

18. The method of claim 15 wherein the first stent, the tubular conduit and the second stent are provided for unidirectionally passing fluid through the prosthesis and at least inhibiting retrograde flow through the prosthesis.

19. The method of claim 15 further comprising expanding the first stent into engagement with the aortic annulus.

20. The method of claim 15 further comprising positioning the second stent in the subject'"'"'s ascending aorta.