Drug Delivery Device and Method for Use with Prosthetic Device Implantation
First Claim
1. An implantable drug delivery device adapted to be installed at or adjacent an implantable orthopedic prosthetic device inserted onto a surgically prepared bone section of a human or other animal, comprising:
- a body having a core formed from a non-biodegradable material formed in the shape of a sleeve and having an inner surface and an outwardly directed outer surface; and
wherein said outer surface has a drug formulation for release thereof into the body of the animal following implantation of the prosthetic device within the body of the animal.
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Accused Products
Abstract
Implantable drug delivery devices are provided which are adapted to be installed adjacent to at least a portion of an orthopedic prosthetic device implanted on a surgically prepared bone section of a patient. For example, the prosthetic device may be a hip joint replacement or knee joint replacement. The drug delivery device may include a body having a core formed from a non-biodegradable material formed in the shape of a sleeve and having an inner surface and an outwardly directed outer surface, wherein the outer surface has a drug formulation for release thereof into the body of the animal following implantation of the prosthetic device within the body of the animal. The outer surface may define one or more pockets for holding the drug formulation.
53 Citations
24 Claims
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1. An implantable drug delivery device adapted to be installed at or adjacent an implantable orthopedic prosthetic device inserted onto a surgically prepared bone section of a human or other animal, comprising:
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a body having a core formed from a non-biodegradable material formed in the shape of a sleeve and having an inner surface and an outwardly directed outer surface; and wherein said outer surface has a drug formulation for release thereof into the body of the animal following implantation of the prosthetic device within the body of the animal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. An implantable drug delivery device adapted to be installed at or adjacent an implantable orthopedic prosthetic device inserted onto a surgically prepared bone section of a human or other animal, comprising:
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a body having a radially inwardly directed inner surface defining an aperture, and a radially outwardly directed outer surface, and said body defining an open shape having two free ends; said body having a thickness dimension defined in a generally radial direction extending from said inner surface to said outer surface; wherein said aperture extends over the length of the thickness dimension; and
wherein said outer surface holds a drug formulation for release thereof into the body of the animal following implantation of the prosthetic device within the body of the animal. - View Dependent Claims (13, 14, 15, 16, 17, 18)
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19. An implantable drug delivery device adapted to be installed on an implantable orthopedic prosthetic device inserted onto a surgically prepared bone section of a human or other animal, comprising:
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a body having a first wall and an outer surface defining at least one pocket for holding a drug formulation, said first wall adapted to be cemented to at least one of a portion of said implantable prosthetic device or said surgically prepared bone section; an aperture formed in said body and extending through said body, said aperture adapted to receive a portion of said implantable prosthetic device; and said at least one pocket holds a drug formulation for release thereof into the body of the animal following implantation of the prosthetic device within the body of the animal. - View Dependent Claims (20, 21, 22, 23)
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24. A method of delivering a drug to a human or other animal having an implantable orthopedic prosthetic device, comprising:
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implanting the orthopedic prosthetic device onto a surgically prepared bone section of the human or other animal; providing an implantable drug delivery device having an aperture; and surrounding a portion of the implanted prosthetic device with the aperture of the implantable drug delivery device in a manner preventing relative motion between the prosthetic device and the drug delivery device.
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Specification