×

Methods of Detection of Changes in Cells

  • US 20090130703A1
  • Filed: 12/15/2008
  • Published: 05/21/2009
  • Est. Priority Date: 09/22/2003
  • Status: Active Grant
First Claim
Patent Images

1. A method of detection of responses of cells to stimuli comprising:

  • (a) (i) immobilizing one or more extracellular matrix ligands to a surface of a colorimetric resonant reflectance biosensor or a grating-based waveguide biosensor, wherein the cells have cell surface receptors specific for the one or more extracellular matrix ligands; and

    adding the cells to the biosensor;

    or(ii) mixing cells with one or more extracellular matrix ligands, wherein the cells have cell surface receptors specific for the one or more extracellular matrix ligands; and

    adding the cells with one or more extracellular matrix ligands to a surface of a colorimetric resonant reflectance biosensor or a grating-based waveguide biosensor;

    (b) exposing the cells to stimuli; and

    (d) detecting the response of the cells to the stimuli.

View all claims
  • 2 Assignments
Timeline View
Assignment View
    ×
    ×