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VITAMIN D DERIVATIVES ACTIVE ON THE VITAMIN D NUCLEAR RECEPTOR, PREPARATION AND USES THEREOF

  • US 20090131378A1
  • Filed: 09/28/2005
  • Published: 05/21/2009
  • Est. Priority Date: 09/28/2005
  • Status: Active Grant
First Claim
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1. A compound presenting the following formula (I):

  • wherein R1 represents a group selected from a hydrogen atom, a halogen atom, a linear or branched (C1-C10)alkyl, an (C1-C10)alkoxy, C2-C10 branched or linear alkenyl or C2-C10 branched or linear alkynyl, an (C5-C14)aryl, and an (C5-C14)aryloxy group, in which said group is optionally substituted by at least one halogen atom, hydroxyl or —

    NH2 group;

    and wherein R represents in which Z represents wherein;

    R2 and R3, identical or different, represent a group selected from H, halogen atom, a C1-C10 branched or linear alkyl, C2-C10 branched or linear alkenyl or C2-C10 branched or linear alkynyl group;

    R4 and R5, identical or different, represent a group selected from H, halogen atom, a C1-C6 linear or branched alkyl, C2-C10 branched or linear alkenyl or C2-C10 branched or linear alkynyl group;

    m represents an integer comprised between 0 and 5 inclusive; and

    n represents an integer comprised between 0 and 5 inclusive.

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