Method for synthesizing polymer on substrate

• US 20090131635A1
• Filed: 07/30/2008
• Published: 05/21/2009
• Est. Priority Date: 07/30/2007
• Status: Abandoned Application

• Current Assignee: Samsung Electronics Co. Ltd. (Samsung Group)
• Original Assignee: Samsung Electronics Co. Ltd. (Samsung Group)
• Inventors: Kim, Won-Sun, Hah, Jung-Hwan, Jung, Sun-Ok, Chi, Sung-Min, Kim, Kyoung-Seon, Ryoo, Man-Hyoung
• Application Number:
  US12/220,923
• Publication Number:
  US 20090131635A1
• Time in Patent Office: Days
• US Class Current: 530/333
• CPC Class Codes: B01J 19/0046 Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays synthesis methods per se C40B50/00
• CPC Class Codes: B01J 2219/00484 by shaking, vibrating or oscillating of the reaction vessels
• CPC Class Codes: B01J 2219/00493 by sparging or bubbling with gases
• CPC Class Codes: B01J 2219/00527 Sheets
• CPC Class Codes: B01J 2219/00529 DNA chips
• CPC Class Codes: B01J 2219/00612 the surface being inorganic
• CPC Class Codes: B01J 2219/00722 Nucleotides
• CPC Class Codes: B01J 2219/00725 Peptides
• CPC Class Codes: H01L 21/67126 Apparatus for sealing, encapsulating, glassing, decapsulating or the like processes H01L23/02, H01L23/28
• CPC Class Codes: H01L 21/6715 Apparatus for applying a liquid, a resin, an ink or the like H01L21/67126 takes precedence

Abstract

For synthesizing a polymer, a substrate is placed within a reaction chamber, and a polymer synthesis sample is fed into the reaction chamber for forming the polymer on the substrate. In addition, the reaction chamber is shaken during formation of the polymer on the substrate within the reaction chamber for increased reaction yield. In addition, forming bubbles of the inactive gas in the polymer synthesis sample during formation of the polymer on the substrate further increases reaction yield.

Claims

1. A method of synthesizing a polymer, the method comprising:

placing a substrate within a reaction chamber;

feeding a polymer synthesis sample into the reaction chamber for forming the polymer on the substrate; and

shaking the reaction chamber during formation of the polymer on the substrate within the reaction chamber.

2. The method of claim 1, wherein the reaction chamber includes a chamber body and a chamber cover that is combined with the chamber body to form a sealed reaction space.

3. The method of claim 2, further comprising:

sealing the reaction space with an edge of the substrate abutting a rim of one of the chamber body or the chamber cover.

4. The method of claim 3, wherein the reaction space is formed between the chamber cover and one surface of the substrate when the edge of the substrate abuts the rim of the chamber cover.

5. The method of claim 4, wherein an air space is formed between the chamber body and another surface of the substrate.

6. The method of claim 5, wherein the reaction space is sealed from the air space.

7. The method of claim 4, wherein another surface of the substrate abuts the chamber body.

8. The method of claim 4, wherein the chamber cover includes a transparent portion for viewing into the reaction space.

9. The method of claim 4, wherein the chamber cover includes at least one opening spatially coupled to at least one fluid inlet/outlet.

10. The method of claim 9, wherein the polymer synthesis sample is fed into the reaction space through the at least one opening.

11. The method of claim 10, further comprising:

feeding an inactive gas into the reaction chamber through the at least one fluid inlet/outlet for generating bubbles in the polymer synthesis sample within the reaction chamber during formation of the polymer.

12. The method of claim 11, wherein the polymer synthesis sample is drained through the at least one fluid inlet/outlet after formation of the polymer on the substrate.

13. The method of claim 4, wherein a distance of the reaction space between the chamber cover and the surface of the substrate is in a range of from about 0.2 mm (millimeters) to about 10 mm (millimeters).

14. The method of claim 3, wherein the reaction space is formed between the chamber body and one surface of the substrate.

15. The method of claim 2, wherein the polymer synthesis sample fills from about 10% to about 90% of the reaction space as the reaction chamber is shaken during formation of the polymer on the substrate.

16. The method of claim 15, wherein the polymer synthesis sample fills about 60% of the reaction space as the reaction chamber is shaken during formation of the polymer on the substrate.

17. The method of claim 1, further comprising:

feeding an inactive gas into the reaction chamber for generating bubbles in the polymer synthesis sample within the reaction chamber during formation of the polymer.

18. The method of claim 1, wherein the step of shaking of the reaction chamber includes:

rolling the reaction chamber with a maximum angle in a range of from about ±

10°

to about ±

60°

.

19. The method of claim 18, wherein the reaction chamber rolls with the maximum angle of about ±

30°

.

20. The method of claim 1, wherein the polymer is a biopolymer that is one of a nucleoside, a nucleotide, an amino acid, or a peptide, and wherein the substrate is one of a semiconductor wafer or a glass substrate.