OPTIMIZED METHOD FOR LID BIOSENSOR RESONANCE DETECTION
First Claim
1. An optical interrogation system comprising:
- a launch system that emits an optical beam towards a biosensor;
a receive system that collects an optical beam from the biosensor and then outputs a signal which corresponds to the collected optical beam; and
a processor that applies a low pass filter to the signal to digitally remove a plurality of problematic parasitic reflections located on each side of an optical resonance represented within the signal.
1 Assignment
0 Petitions
Accused Products
Abstract
An optical interrogation system is described herein that can interrogate a label-independent-detection (LID) biosensor and monitor a biological event on top of the biosensor without suffering from problematical parasitic reflections and/or problematical pixelation effects. In one embodiment, the optical interrogation system is capable of interrogating a biosensor and using a low pass filter algorithm to digitally remove problematic parasitic reflections contained in the spectrum of an optical resonance which makes it easier to determine whether or not a biological event occurred on the biosensor. In another embodiment, the optical interrogation system is capable of interrogating a biosensor and using an oversampling/smoothing algorithm to reduce oscillations in the estimated location of an optical resonance caused by the problematical pixelation effect which makes it easier to determine whether or not a biological event occurred on the biosensor.
-
Citations
20 Claims
-
1. An optical interrogation system comprising:
-
a launch system that emits an optical beam towards a biosensor; a receive system that collects an optical beam from the biosensor and then outputs a signal which corresponds to the collected optical beam; and a processor that applies a low pass filter to the signal to digitally remove a plurality of problematic parasitic reflections located on each side of an optical resonance represented within the signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
-
-
12. A method for interrogating a biosensor, said method comprising the steps of:
-
emitting an optical beam towards the biosensor; collecting an optical beam from the biosensor; generating a signal which corresponds to the collected optical beam; and applying a low pass filter to the signal to digitally remove a plurality of problematic parasitic reflections located on each side of an optical resonance represented within the signal. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20)
-
Specification