Solid peptide preparations for inhalation and their preparation
First Claim
Patent Images
1. A process for preparing a fine particulate protein substance or substance mixture, said fine particulate protein substance or substance mixture having a particle size in the nanometer to micrometer range, said process comprises:
- grinding a protein substance or substance mixture at a low temperature in a suspending medium, said low temperature being lower than −
30°
C., wherein said suspending medium is gaseous at ambient pressure and temperature; and
removing said suspending medium.
0 Assignments
0 Petitions
Accused Products
Abstract
The invention relates to solid pharmaceutical preparations, in particular for inhalatory administration in mammals, their preparation and their use such as, for example, in powder inhalers.
-
Citations
23 Claims
-
1. A process for preparing a fine particulate protein substance or substance mixture, said fine particulate protein substance or substance mixture having a particle size in the nanometer to micrometer range, said process comprises:
-
grinding a protein substance or substance mixture at a low temperature in a suspending medium, said low temperature being lower than −
30°
C., wherein said suspending medium is gaseous at ambient pressure and temperature; andremoving said suspending medium. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 19, 20, 21, 22)
-
- 13. A process for applying a fine-particulate substance or substance mixture to a carrier material, which comprises stripping off by thorough mixing the suspending medium from a suspension of said fine particulate substance or substance mixture, said carrier material and said substance or substance mixture being substantially insoluble in said suspending medium.
Specification