ANALYTE SENSOR
First Claim
Patent Images
1. An electrochemical analyte sensor comprising:
- at least one electrode having an electroactive surface;
an interference layer comprising a cellulosic derivative in contact with at least a portion of the electroactive surface;
an enzyme layer in contact with at least a portion of the interference layer, anda membrane comprising vinyl ester monomeric units, the membrane covering at least a portion of the enzyme layer, at least a portion of the interference layer and at least a portion of the electroactive surface.
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Abstract
Electrochemical sensors for measuring an analyte in a subject are described. More particularly, devices for measurement of an analyte are disclosed incorporating a sensor comprising an enzyme layer in contact with an interference layer and a membrane comprising vinyl ester monomeric units covering at least a portion of the enzyme layer and at least a portion of the interference layer, the devices providing rapid and accurate analyte levels upon deployment.
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Citations
75 Claims
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1. An electrochemical analyte sensor comprising:
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at least one electrode having an electroactive surface; an interference layer comprising a cellulosic derivative in contact with at least a portion of the electroactive surface; an enzyme layer in contact with at least a portion of the interference layer, and a membrane comprising vinyl ester monomeric units, the membrane covering at least a portion of the enzyme layer, at least a portion of the interference layer and at least a portion of the electroactive surface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. An electrochemical analyte sensor comprising:
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at least one conductive ink electrode, the at least one conductive ink electrode having an electroactive surface; a cellulose acetate butyrate layer in contact with at least a portion of the electroactive surface; an enzyme layer comprising poly-N-vinylpyrrolidone and glucose oxidase, the enzyme layer in contact with at least a portion of the cellulose acetate butyrate layer, and a polyethylene vinyl acetate membrane covering the enzyme layer, the cellulose acetate butyrate layer and at least a portion of the electroactive surface.
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24. An electrochemical analyte sensor comprising:
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at least one electrode having an electroactive surface; an interference layer comprising a cellulosic derivative in contact with at least a portion of the electroactive surface; an enzyme layer in contact with at least a portion of the interference layer; and a membrane comprising vinyl ester monomeric units, the membrane covering the enzyme layer, the interference layer and at least a portion of the electroactive surface. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45)
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46. A electrochemical analyte sensor assembly comprising:
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a flex circuit comprising at least one reference electrode and at least one working electrode, the at least one working electrode having an electroactive surface capable of providing a detectable electrical output upon interaction with an electrochemically detectable species; an interference layer comprising a cellulosic derivative in contact with at least a portion of the electroactive surface; an enzyme layer in contact with at least a portion of the interference layer, and a membrane comprising vinyl ester monomeric units, the membrane covering the enzyme layer, the interference layer and at least a portion of the electroactive surface of the working electrode; wherein the flex circuit is electrically configurable to a control unit capable of at least receiving the detectable electrical output. - View Dependent Claims (47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75)
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Specification