Guidewire with adjustable stiffness

• US 20090143769A1
• Filed: 11/14/2008
• Published: 06/04/2009
• Est. Priority Date: 04/23/2007
• Status: Abandoned Application

• Current Assignee: CardioGuidance Biomedical, LLC
• Original Assignee: Interventional & Surgical Innovations, LLC
• Inventors: Parodi, Juan Carlos, Mooney, Ivan, Donohue, Colin, Hinchliffe, Peter W.J., Lupton, Henry
• Application Number:
  US12/291,851
• Publication Number:
  US 20090143769A1
• Time in Patent Office: Days
• US Class Current: 604/528
• CPC Class Codes: A61M 2025/0006 which can be secured against axial movement, e.g. by using a locking cuff
• CPC Class Codes: A61M 2025/0042 Microcatheters, cannula or the like having outside diameters around 1 mm or less
• CPC Class Codes: A61M 2025/09075 having a core without a coil possibly combined with a sheath
• CPC Class Codes: A61M 2025/09083 having a coil around a core
• CPC Class Codes: A61M 2025/09091 where a sheath surrounds the coil at the distal part
• CPC Class Codes: A61M 2025/09116 Design of handles or shafts or gripping surfaces thereof for manipulating guide wires
• CPC Class Codes: A61M 2025/09133 having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
• CPC Class Codes: A61M 2025/0915 having features for changing the stiffness
• CPC Class Codes: A61M 2025/09175 having specific characteristics at the distal tip
• CPC Class Codes: A61M 25/09 Guide wires
• CPC Class Codes: A61M 25/09025 with sliding mandrils

Abstract

A medical guidewire system comprising a first inner member having a first outer diameter, a second intermediate member having a second outer diameter larger than the first outer diameter, and a third outer member having a third diameter larger than the second outer diameter of the second member. The second member has a longitudinal extending opening to receive the first member for sliding movement with respect to the first member and the third outer member has a longitudinally extending opening to receive the second member for sliding movement with respect to the first and second member. The first member has a first stiffness, the third member has a third stiffness greater than the first stiffness, and the second member is movable to stiffen the guidewire system.

Claims

1-21. -21. (canceled)

22. A medical guidewire system comprising a core wire, a first tube and a second tube, the first tube having a second diameter larger than a first diameter of the core wire and including a distal region having a greater flexibility than a flexibility of a proximal region, the second tube having a third diameter larger than the second diameter, the second tube having a distal region having a greater flexibility than a flexibility of a proximal region, the first tube having a longitudinally extending opening to receive the core wire for relative sliding movement, the second tube having a longitudinally extending opening to receive the first tube for relative sliding movement, the first tube configured to increase the stiffness of a distal end of the second tube.

23. The guidewire system of claim 22, wherein the core wire includes a solid core for at least a majority of its length.

24. The guidewire system of claim 22, wherein the first tube has a slotted region in at least the distal region.

25. The guidewire system of claim 22, wherein the second tube has a slotted region in at least the distal region.

26. The guidewire system of claim 24, wherein distal slots of the first tube are closer together than more proximal slots.

27. The guidewire system of claim 25, wherein distal slots of the second tube are closer together than more proximal slots.

28. The guidewire system of claim 25, wherein the second tube has a plurality of interrupted slots.

29. The guidewire system of claim 24, wherein the first tube has a plurality of interrupted slots.

30. The guidewire system of claim 22, wherein the first tube is positionable in the second tube in a retracted position and a fully advanced position, in the fully advanced position, a distalmost tip of the first tube does not extend distal of a distalmost tip of the second tube.

31. The guidewire system of claim 22, wherein the core wire has a handle configured and dimensioned to receive a catheter thereover.

32. A medical guidewire system comprising:

an inner member having a first diameter and a first stiffness;

a stiffener member having a second diameter larger than the first diameter and having a second stiffness greater than the first stiffness; and

an outer member having a third diameter larger than the second diameter and having a third stiffness greater than the first stiffness and less than the second stiffness, the stiffener member being slidable over the inner member and slidable within the outer member to increase the stiffness of the outer member.

33. The guidewire system of claim 32, wherein the outer member comprises a tube with a least one slot in a distal region to provide a more flexible distal region.

34. The guidewire system of claim 33, wherein the stiffener member comprises a tube with a least one slot in a distal region to provide a more flexible distal region.

35. The guidewire system of claim 32, wherein the stiffener member comprises a tube with a least one slot in a distal region to provide a more flexible region.

36. A medical guidewire system comprising:

an inner member having a first diameter and a first stiffness;

a stiffener member having a proximal end and a distal end and a second diameter larger than the first diameter, the stiffener having a second stiffness greater than the first stiffness; and

an outer member having a third diameter larger than the second diameter and having a third stiffness greater than the first stiffness, the outer member having a proximal end and a distal end, the stiffener being positioned within the outer member for relative sliding movement for positioning in a proximal position with respect to the outer member and a fully advanced distal position with respect to the outer member, wherein in the distal position a distalmost tip of the stiffener member does not extend distal of a distalmost tip of the outer member.

37. The guidewire system of claim 36, wherein the outer member includes an internal shoulder, the shoulder creating a stop to limit distal advancement of the stiffener member.

38. The guidewire system of claim 36, wherein the outer member has a lumen, the lumen having a reduced diameter area in a distal area to ease the movement of the inner member to an advanced position where a distalmost tip of the inner member is positioned distal of a distalmost tip of the outer member.

39. The guidewire system of claim 36, wherein the inner member is advanceable to a position wherein a distalmost tip of the inner member is positioned distally of the distalmost tip of the outer member.

40. The guidewire system of claim 36, wherein a distal end of the outer member tapers to a transverse dimension close to the first diameter of the inner member

41. A medical guidewire system comprising:

an inner member having a first diameter and a first stiffness;

a stiffener member having a second diameter larger than the first diameter and having a second stiffness greater than the first stiffness; and

an outer member having a third diameter larger than the second diameter, the outer member having a lumen dimensioned to receive the stiffener member, a distal portion of the lumen having a first transverse dimension less than a second transverse dimension of a more proximal portion to reduce a gap between the inner member and outer member when the inner member is advanced so a distalmost tip extends distally of a distalmost tip of the outer member, the first transverse dimension being less than the second diameter of the stiffener member.

42. The guidewire system of claim 41, wherein the distalmost tip of the outer member is tapered.

43. The guidewire system of claim 41, wherein an inner wall of the lumen is angled inwardly to transition from the second transverse dimension to the first transverse dimension.

44. The guidewire system of claim 41, wherein the second stiffness of the stiffener member is greater than a third stiffness of the outer member.

45. The guidewire system of claim 41, wherein the inner and outer members comprise tubes with slotted regions.

50. The guidewire system of claim 45, wherein the first and second handles interlock.

51. The guidewire system of claim 50, wherein the second handle includes a collar to compress a collet on the inner member to fix the position of the inner member and intermediate member.

46. A medical guidewire system comprising:

an inner member having a first diameter and a first stiffness, the inner member being dimensioned for passage of a catheter thereover;

an intermediate member having a second handle, a second diameter larger than the first diameter and having a second stiffness greater than the first stiffness; and

an outer member having a third handle, a third diameter larger than the second diameter and a third stiffness greater than the first stiffness, the outer member having a lumen dimensioned to receive the stiffener, wherein the first, second and third handles are dimensioned to receive a catheter thereover.

47. The guidewire system of claim 46, wherein the inner member has a first handle, the first handle being cylindrically shaped.

48. The guidewire system of claim 47, wherein the second and third handles are cylindrically shaped.

49. The guidewire system of claim 46, wherein the second and third handles are cylindrically shaped.

52. A medical guidewire system comprising:

an inner member having a first diameter and a first stiffness;

a stiffener member having a second diameter larger than the first diameter and having a second stiffness greater than the first stiffness, the stiffener member further including a clamping member to apply a clamping force to a portion of the inner member to fix the position of the inner member with respect to the stiffener member; and

an outer member having a third diameter larger than the second diameter and having a third stiffness greater than the first stiffness, the outer member having a lumen dimensioned to receive the stiffener member.

53. The guidewire system of claim 52, wherein the clamping member comprises a collar and the portion of the inner member comprises a collet, the collar applying a clamping force to the collet

54. The guidewire system of claim 52, wherein the lumen of the outer member has a reduced diameter in a distal region.

55. The guidewire system of claim 52, wherein the clamping member is dimensioned to receive a catheter thereover.

56. The guidewire system of claim 52, wherein the clamping member is configured to fix the position of the inner member at a number of selected positions of the inner member with respect to the stiffener member.

57. A medical guidewire system having a transverse dimension and comprising an inner member, an intermediate member and an outer member, the guidewire having first, second and third guidewire stiffnesses, wherein the first guidewire stiffness is achieved by advancement of a distalmost tip of the inner member beyond a distalmost tip of the outer member, the second guidewire stiffness is achieved by the inner member and intermediate member being positioned in a retracted position with respect to the outer member, and the third guidewire stiffness is achieved by advancing the intermediate member and without changing the transverse dimension of the guidewire, the third guidewire stiffness being greater than the second guidewire stiffness.

58. The guidewire system of claim 57, wherein the inner member includes a handle at a proximal region, the handle dimensioned to receive a catheter thereover.

59. The guidewire system of claim 57, wherein the intermediate member includes a handle at a proximal region, the handle dimensioned to receive a catheter thereover.

60. The guidewire system of claim 57, wherein in the advanced position of the intermediate member, a distalmost tip of the intermediate member does not extend distal of a distalmost tip of the outer member.

61. The guidewire system of claim 57, wherein the intermediate and outer members comprises a hypotube with a series of slots formed in a sidewall to increase flexibility.

62. The guidewire system of claim 61, wherein the space between the slots increases toward a proximal end of the hypotube.

63. A guidewire system having an inner member having a first outer diameter and a first stiffness, an outer member having a third diameter larger than the first diameter, and a stiffener member positioned between the inner and outer members and having a second outer diameter larger than the first outer diameter and smaller than the third diameter and having a second stiffness greater than the first stiffness, wherein the inner member and stiffener member are movable relative to one another and the inner member and stiffener member are selectively lockable to fix a position of the inner member relative to the stiffener member in a position proximal to a fully advanced position with respect to the outer member.

64. The guidewire system of claim 63, wherein the inner member and stiffener member are selectively by selectively applying a clamping force on an outer surface portion of the inner member.