Strategies for gene expression analysis
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Abstract
The invention provides methods for screening compound or chemical libraries by analyzing expressed RNA samples from biological samples treated with members of a compound library in a high throughput format.
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Citations
57 Claims
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1-50. -50. (canceled)
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51. A hybridization system comprising:
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(a) an array comprising a plurality of nucleic acids corresponding to at least 500 expressed RNA samples, which expressed RNA samples are each obtained from a different biological sample, wherein each biological sample is contacted with at least one member of a compound library prior to obtaining the plurality of expressed RNA samples; and
,(b) a plurality of defined sequence probes, which defined sequence probes each comprise a different polynucleotide sequence, and which probes are each capable of generating a different detectable signal. - View Dependent Claims (52, 53, 54, 55, 56, 57)
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Specification