Implantable device for drug delivery and improved visibility
First Claim
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1. An implantable device as a delivery device for at least one therapeutic agent being composed of at least one type of base material comprising at least two types of reservoirs for at least one therapeutic agent whereby each type of reservoir independently provides identical or different release rates for the at least one therapeutic agent.
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Abstract
The present invention provides an implantable device as delivery device for at least one therapeutic agent being composed of at least one type of base material comprising at least two types of reservoirs for at least one therapeutic agent whereby each type of reservoir independently provides identical or different release rates for the at least one therapeutic agent.
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Citations
39 Claims
- 1. An implantable device as a delivery device for at least one therapeutic agent being composed of at least one type of base material comprising at least two types of reservoirs for at least one therapeutic agent whereby each type of reservoir independently provides identical or different release rates for the at least one therapeutic agent.
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10. An implantable device characterized in that the implantable device comprises at least one therapeutic composition within at least two different reservoirs for the at least one therapeutic agent wherein the therapeutic composition is directly affixed to a surface structure of the implantable device as a biodegradable or porous or permeable non-biodegradable coating;
- the therapeutic composition is contained within openings in the implantable device; and
/or the therapeutic composition is impregnated in the base material of the implantable device. - View Dependent Claims (11, 12, 13, 14)
- the therapeutic composition is contained within openings in the implantable device; and
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20. Use of composition loaded on an implantable device as a delivery device for at least one therapeutic agent being composed of at least one type of base material comprising at least two types of reservoirs for at least one therapeutic agent whereby each type of reservoir independently provides identical or different release rates for the at least one therapeutic agent for the treatment of cancer, atherosclerosis and angiogenesis-dependent diseases.
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21. Use of composition loaded on an implantable device as a delivery device for at least one therapeutic agent being composed of at least one type of base material comprising at least two types of reservoirs for at least one therapeutic agent whereby each type of reservoir independently provides identical or different release rates for the at least one therapeutic agent for use in medical applications such surgery, bone-replacement, prosthodontics, dental roots, crowns and orthopedic joints.
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22. Use of composition loaded on an implantable device as a delivery device for at least one therapeutic agent being composed of at least one type of base material comprising at least two types of reservoirs for at least one therapeutic agent whereby each type of reservoir independently provides identical or different release rates for the at least one therapeutic agent for the treatment of antimicrobial resistance.
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23. A device suitable for implantation in a living animal comprising a first region and at least a second region wherein the first region is of a material having a first response characteristic to electromagnetic radiation and the second region has a second response characteristic to electromagnetic radiation different to said first response characteristic, characterized in that the second region is incorporated into the structure of the device to provide, at least temporarily, substantially the same physical properties as if it were fabricated of the first material but because of its differing response characteristic to electromagnetic radiation provides an improved image generating capability in relation to an imaging technique used for internally imaging the device in the living animal compared with if the second region was fabricated of the first material.
- 24. A stent for implantation in a lumen of a patient characterized in that said stent comprises a plurality of first supporting regions having metal lumen wall supporting means and at least one second supporting region within or between the metal supporting regions, the second supporting region comprising a structural polymer lumen wall supporting means.
- 29. An implantable device for implantation in a patient characterized that the device comprises a metallic structure having windows therein filled by a polymer.
- 34. A device for implantation in the body of an animal characterized that it includes a composite material comprising a polymer and drug eluting fibers.
- 36. A stent characterized in that it comprises a self-expanding support structure and a biodegradable drug-eluting layer on an outer surface thereof wherein the self expanding support structure expands after insertion into a patient as the coating is adsorbed into the patient.
Specification