Biosensor Measurement Machine , Biosensor Measurement System and Biosensor Measurement Method

• US 20090152127A1
• Filed: 09/08/2006
• Published: 06/18/2009
• Est. Priority Date: 09/14/2005
• Status: Active Grant

• Current Assignee: National Institute of Advanced Industrial Science and Technology (Government of Japan), Sumitomo Electric Industries Limited (Sumitomo Corporation)
• Original Assignee: National Institute of Advanced Industrial Science and Technology (Government of Japan), Sumitomo Electric Industries Limited (Sumitomo Corporation)
• Inventors: Nakamura, Hideaki, Gotoh, Masao, Karube, Isao, Ishikawa, Tomoko, Hosoya, Toshifumi, Kitamura, Takahiko, Kaimori, Shingo, Ichino, Moriyasu
• Granted Patent: US 8,282,813 B2
• Time in Patent Office: Days
• US Class Current: 205/777.500
• CPC Class Codes: G01N 27/3273 Devices therefor, e.g. test element readers, circuitry details not specific to biochemical electrodes G01N33/4875

Abstract

Provided are a biosensor chip measurement machine that can obtain accurate measurement results within a short period of time by employing only a tiny amount as a sample, and a measurement method therefor.

A biosensor measurement machine 20 includes a power source 21, which is connected to a voltage regulator 22, a measurement instrument 23, and a controller 24 for supplying power. When a biosensor chip 1 is connected to the biosensor measurement machine 20 and a voltage is applied, the measurement instrument begins the measurement of a current value for a biosensor. When a measured current value or a measured charge value is greater than a reference value, the measurement is ended in accordance with an instruction issued by the controller 24, and when the value is smaller than the reference value, the measurement is continued in accordance with a controller instruction.

Claims

1. A biosensor measurement machine comprising:

a voltage application unit for applying a voltage to a biosensor chip;

a measurement unit for measuring a current or a charge generated by the voltage application unit; and

a control unit for determining whether a measurement should be continued, based on a current value or a charge value measured by the measurement unit.

2. The biosensor measurement machine according to claim 1, wherein

the control unit compares the current value or the charge value with a reference value therefor to determine whether the measurement should be continued, and

a plurality of different values are prepared for use as reference values.

3. The biosensor measurement machine according to claim 1, wherein

the control unit also includes a plurality of different standard curve tables.

4. A biosensor measurement system comprising:

a biosensor measurement machine according to claim 1, and

a biosensor chip.

5. The biosensor measurement system according to claim 4, wherein

a biosensor chip includes glucose oxidase as an enzyme, and has a cavity volume equal to or smaller than 300 nl (nanoliters).

6. A biosensor measurement method comprising the steps of:

applying a voltage to a biosensor chip;

measuring a current or a charge generated by application of the voltage; and

determining whether a measurement should be continued, based on a current value or a measured charge value.