NEUROMODULATORY METHODS FOR TREATING PULMONARY DISORDERS
First Claim
1. A method for treating a pulmonary disorder in a subject, said method comprising the steps of:
- inserting a therapy delivery device into a vessel of the subject;
advancing the therapy delivery device to a point substantially adjacent an intraluminal target site of the autonomic nervous system (ANS); and
activating the therapy delivery device to delivery a therapy signal to the intraluminal target site of the ANS to treat the pulmonary disorder;
wherein the intraluminal target site is in electrical communication with nervous tissue selected from the group consisting of a spinal nerve, a postganglionic fiber of a spinal nerve, a sympathetic chain ganglion, a thoracic sympathetic chain ganglion, a cervical ganglion, a lower cervical ganglion, an inferior cervical ganglion, an intramural ganglion, a splanchnic nerve, an esophageal plexus, a cardiac plexus, a pulmonary plexus, an anterior pulmonary plexus, a posterior pulmonary plexus, a celiac plexus, a hypogastric plexus, an inferior mesenteric ganglion, a celiac ganglion, and a superior mesenteric ganglion.
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Accused Products
Abstract
A method for treating a pulmonary disorder in a subject includes inserting a therapy delivery device into a vessel of the subject, advancing the therapy delivery device to a point adjacent an intraluminal target site of the autonomic nervous system, and activating the therapy delivery device to delivery a therapy signal to the intraluminal target site to treat the pulmonary disorder. The intraluminal target site is in electrical communication with nervous tissue selected from the group consisting of a spinal nerve, a postganglionic fiber of a spinal nerve, a sympathetic chain ganglion, a thoracic sympathetic chain ganglion, a cervical ganglion, a lower cervical ganglion, an inferior cervical ganglion, an intramural ganglion, a splanchnic nerve, an esophageal plexus, a cardiac plexus, a pulmonary plexus, an anterior pulmonary plexus, a posterior pulmonary plexus, a celiac plexus, a hypogastric plexus, an inferior mesenteric ganglion, a celiac ganglion, and a superior mesenteric ganglion.
80 Citations
24 Claims
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1. A method for treating a pulmonary disorder in a subject, said method comprising the steps of:
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inserting a therapy delivery device into a vessel of the subject; advancing the therapy delivery device to a point substantially adjacent an intraluminal target site of the autonomic nervous system (ANS); and activating the therapy delivery device to delivery a therapy signal to the intraluminal target site of the ANS to treat the pulmonary disorder; wherein the intraluminal target site is in electrical communication with nervous tissue selected from the group consisting of a spinal nerve, a postganglionic fiber of a spinal nerve, a sympathetic chain ganglion, a thoracic sympathetic chain ganglion, a cervical ganglion, a lower cervical ganglion, an inferior cervical ganglion, an intramural ganglion, a splanchnic nerve, an esophageal plexus, a cardiac plexus, a pulmonary plexus, an anterior pulmonary plexus, a posterior pulmonary plexus, a celiac plexus, a hypogastric plexus, an inferior mesenteric ganglion, a celiac ganglion, and a superior mesenteric ganglion. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method for treating a pulmonary disorder in a subject, said method comprising the steps of:
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inserting a therapy delivery device into a vessel of the subject; advancing the therapy delivery device to a point substantially adjacent an intraluminal target site of the ANS; and activating the therapy delivery device to delivery a therapy signal to the intraluminal target site of the ANS to treat the pulmonary disorder; wherein the pulmonary disorder is selected from the group consisting of asthma, chronic obstructive pulmonary disease, cystic fibrosis, bronchiolitis, pneumonia, pulmonary thromboembolism, bronchitis, emphysema, adult respiratory distress syndrome, allergies, brochiectasis, bronchopulmonary displasia, Chlamydia pneumionia, chronic bronchitis, chronic lower respiratory diseases, croup, familial emphysema, high altitude pulmonary edema, idiopathic pulmonary fibrosis, interstitial lung disease, lymphangioleiomyomatosis, neonatal respiratory distress syndrome, parainfluenza, pleural effusion, pleurisy, pneumothorax, primary pulmonary hypertension, psittacosis, pulmonary edema, pulmonary embolism, pulmonary hypertension, Q fever, respiratory failure, respiratory syncytial virus, sarcoidosis, SARS, smoking, stridor, tuberculosis, and acute respiratory distress syndrome. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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Specification