Integrated Sensor for Analyzing Biological Samples

• US 20090159444A1
• Filed: 08/04/2008
• Published: 06/25/2009
• Est. Priority Date: 11/30/2005
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories)
• Inventors: Cabrall, John J., Matula, Scott A., Petyt, Adrian, Nicholls, Clive, Chambers, Geoffrey Roger, Hector, Simon Andrew, Prieto, Javier, Ghesquiere, Alexander
• Granted Patent: US 8,070,692 B2
• Time in Patent Office: Days
• US Class Current: 204/403.20
• CPC Class Codes: A61B 2562/0295 Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150519 Details of construction of hub, i.e. element used to attach the single-ended needle to a piercing device or sampling device
• CPC Class Codes: A61B 5/150564 Protectors removed by pulling or pushing
• CPC Class Codes: A61B 5/150572 Pierceable protectors, e.g. shields, caps, sleeves or films, e.g. for hygienic purposes
• CPC Class Codes: A61B 5/150702 fully automatically removed, i.e. the removing does not require any action by the user
• CPC Class Codes: A61B 5/150786 Optical identification systems, e.g. bar codes, colour codes
• CPC Class Codes: A61B 5/150793 Electrical or magnetic identification means
• CPC Class Codes: A61B 5/15132 comprising tooth-shaped elements, e.g. toothed wheel or rack and pinion
• CPC Class Codes: A61B 5/15153 Multiple piercing elements stocked in a single compartment
• CPC Class Codes: A61B 5/15174 Piercing elements stocked in the form of a stack or pile
• CPC Class Codes: A61B 5/15176 Stocking means comprising cap, cover, sheath or protection for aseptic stocking
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: C12Q 1/006 for glucose
• CPC Class Codes: G01N 33/48757 Test elements dispensed from a stack

Abstract

An integrated lancet and testing striplet for measuring a body analyte level in a health care regimen includes a skin piercing member and an analyte sensor coupled together.

Claims

1. An analyte test strip for measuring a body glucose level in a diabetes care regimen, comprising:

(a) a base;

(b) a cover;

(c) multiple electrodes including a working electrode applied to one or more major surfaces of the cover;

(d) a layer of electrically conductive material applied to a major surface of the base;

(e) a sample flow channel including assay chemistry for testing a glucose level of an applied body fluid; and

(f) at least one layer of electrically conductive adhesive for adhering the base to the cover, such that at least one electrical passageway exists from an inner face to an outer face of the cover.

2. The analyte test strip of claim 1, wherein the working electrode and a trigger electrode are positioned in said flow channel.

3. The analyte test strip of claim 1, further comprising electrical contact pads on the outer face of the cover.

4. The analyte test strip of claim 1, further comprising a layer of an electrically conductive material applied to a major surface of the cover.

5. The analyte test strip of claim 1, wherein said working electrode comprises carbon.

6. The analyte test strip of claim 5, further comprising a trigger electrode.

7. The analyte test strip of claim 6, wherein the trigger electrode comprises carbon.

8. The analyte test strip of claim 1, wherein the strip is configured to analyze the analyte in a volume of less than about 1 microliter of sample.

9. The analyte test strip of claim 1, wherein the strip is configured to analyze the analyte in a volume of less than about 0.5 microliter of sample.

10. The analyte test strip of claim 1, wherein the strip is configured to analyze the analyte in a volume of less than about 0.2 microliter of sample.

11. The analyte test strip of claim 1, wherein the analyte comprises glucose.

12. An analyte test strip for measuring a body glucose level in a diabetes care regimen, comprising:

(a) a base;

(b) a cover;

(c) multiple electrodes including a working electrode and a trigger electrode applied to one or more major surfaces of the cover;

(d) a layer of electrically conductive material applied to a major surface of the base;

(e) a sample flow channel including assay chemistry for testing a glucose level of an applied body fluid;

(f) at least one layer of adhesive for adhering the base to the cover; and

(g) one or more electrically conductive vias defined in the cover and forming an electrical passageway from an inner face to an outer face of the cover.

13. The analyte test strip of claim 12, wherein the analyte comprises glucose.

14. The analyte test strip of claim 12, wherein the working electrode and a trigger electrode are positioned in said flow channel.

15. The analyte test strip of claim 12, further comprising electrical contact pads on the outer face of the cover.

16. The analyte test strip of claim 12, further comprising a layer of an electrically conductive material applied to at least one major surface of the cover.

17. The analyte test strip of claim 12, wherein said working electrode comprises carbon.

18. The analyte test strip of claim 17, further comprising a trigger electrode comprising carbon.