METHOD AND REAGENT FOR PRODUCING NARROW, HOMOGENOUS REAGENT STRIPS
First Claim
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1. A process for producing a reagent layer on a solid support material, comprising the steps of:
- providing a solid support material;
moving said solid support material relative to a slot-die-coating head;
maintaining a defined distance between the surface of said solid support material and said slot-die-coating head;
depositing a shear thinning, at least slightly thixotropic reagent through said slot-die-coating head to create a continuous stripe of reagent on said solid support material, wherein said reagent has a viscosity of between about 70 and 130 mPa-s and a surface tension of between about 30 and 50 mN/m; and
drying the coated reagent stripe on said support material.
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Abstract
The present invention concerns a reagent coating mass which can be used in slot-die-coating of flat support materials in the manufacturing processes of test strips. Advantageously, the reagent mass of the invention exhibits certain superior rheological properties such as viscosity, surface tension and thixotropy. The reagent mass is preferably used to coat thin, narrow and homogeneous stripes of reagent material onto flat web material.
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Citations
14 Claims
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1. A process for producing a reagent layer on a solid support material, comprising the steps of:
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providing a solid support material; moving said solid support material relative to a slot-die-coating head; maintaining a defined distance between the surface of said solid support material and said slot-die-coating head; depositing a shear thinning, at least slightly thixotropic reagent through said slot-die-coating head to create a continuous stripe of reagent on said solid support material, wherein said reagent has a viscosity of between about 70 and 130 mPa-s and a surface tension of between about 30 and 50 mN/m; and drying the coated reagent stripe on said support material. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. In a process for preparing biosensors from a webbing of a substrate, the improvement comprising:
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depositing a continuous stripe of reagent onto the webbing in the form of a shear thinning, at least slightly thixotropic reagent having a viscosity of between about 70 and 130 mPa-s and a surface tension of between about 30 and 50 mN/m; and drying the coated reagent stripe on said support material.
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14. A process for preparing biosensors comprising:
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depositing a continuous stripe of reagent onto a webbing in the form of a shear thinning, at least slightly thixotropic reagent having a viscosity of between about 70 and 130 mPa-s and a surface tension of between about 30 and 50 mN/m; applying a spacer layer over the reagent; and attaching the spacer layer to the webbing.
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Specification