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Methods, Kits and Compositions Pertaining to Combination Oligomers and Libraries for Their Preparation

  • US 20090163381A1
  • Filed: 12/26/2006
  • Published: 06/25/2009
  • Est. Priority Date: 03/09/2001
  • Status: Abandoned Application
First Claim
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1. A compound library comprising a bifunctional single set of oligomer blocks that are suitable for producing both terminal oligomer blocks and condensation oligomer blocks by the removal of different protecting groups wherein the oligomer blocks of the bifunctional set are peptide nucleic acid oligomer, PNA chimera or PNA combination oligomer;

  • provided however that;

    (a) the oligomer blocks are selected to comprise functional moieties that form a linker of at least three atoms in length that covalently links the two-oligomer blocks when a terminal oligomer block is condensed with a condensation oligomer block;

    (b) the oligomer blocks are not support bound; and

    (c) the oligomer blocks do not comprise nucleobase-protecting groups.

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