TRANSPULMONARY SYSTEMIC COOLING USING LIQUID MISTS
First Claim
1. A method for transpulmonary cooling, comprising the steps of,selecting a patient suffering from stroke, head trauma, myocardial infarction, or cardiogenic shock;
- providing a liquid having a boiling point of 38-300°
C.;
nebulizing the liquid to form a mist; and
delivering the mist to the airway of a patient so that the patient inhales the mist to cause systemic cooling,wherein delivering the mist is continued until the systemic temperature is reduced to about 35°
C. or below.
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Accused Products
Abstract
A method for transpulmonary cooling by providing a liquid having a boiling point of 38-300° C., more preferably 38-250° C., more preferably 38-200° C., more preferably 38-150° C., more preferably 38-80° C. The liquid is nebulized to form a mist. The mist is optionally cooled below room temperature and delivered to the airway of a patient so that the patient inhales the mist. The mist causes systemic cooling by evaporative heat loss when inhaled at room temperature and additionally by direct heat transfer when inhaled below room temperature. Compositions and medical devices for transpulmonary cooling are also provided.
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Citations
16 Claims
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1. A method for transpulmonary cooling, comprising the steps of,
selecting a patient suffering from stroke, head trauma, myocardial infarction, or cardiogenic shock; -
providing a liquid having a boiling point of 38-300°
C.;nebulizing the liquid to form a mist; and delivering the mist to the airway of a patient so that the patient inhales the mist to cause systemic cooling, wherein delivering the mist is continued until the systemic temperature is reduced to about 35°
C. or below. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method for transpulmonary cooling, comprising the steps of;
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selecting a patient suffering from cerebral ischemia; providing a liquid having a boiling point of 38-300°
C.;nebulizing the liquid to form a mist; and delivering the mist to the airway of a patient so that the patient inhales the mist to cause systemic cooling, wherein delivering the mist is continued until the systemic temperature is reduced to about 35°
C. or below. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16)
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Specification