DETERMINING CANINE proBNP
First Claim
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1. A method of detecting canine proBNP or a fragment thereof in a canine sample comprising(a) providing a canine sample;
- (b) contacting the sample with at least one antibody that binds an epitope in the region from amino acids 32 to 48 of canine proBNP; and
(c) detecting the binding of the antibody to the epitope whereby the canine proBNP or the fragment thereof in the sample is detected.
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Abstract
Methods and compositions are disclosed for determining canine proBNP or fragments thereof in a sample. In one method, canine proBNP or fragments thereof are determined by providing a canine sample, contacting the sample with at least one antibody that binds an epitope in the region from amino acids 32 to 48 of canine proBNP, and determining the presence of the canine proBNP or fragments thereof present in the sample. Antibodies that bind canine proBNP and kits comprising such antibodies are also disclosed.
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Citations
20 Claims
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1. A method of detecting canine proBNP or a fragment thereof in a canine sample comprising
(a) providing a canine sample; -
(b) contacting the sample with at least one antibody that binds an epitope in the region from amino acids 32 to 48 of canine proBNP; and (c) detecting the binding of the antibody to the epitope whereby the canine proBNP or the fragment thereof in the sample is detected. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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- 13. An isolated antibody that binds an epitope in the region from amino acids 32 to 48 of canine proBNP.
- 15. A kit for detecting canine proBNP or a fragment thereof comprising an antibody that binds an epitope in the region from amino acids 32 to 48 of canine proBNP and a label.
Specification