MESHES OF VARIABLE CONSTRUCTION

• US 20090171377A1
• Filed: 12/24/2008
• Published: 07/02/2009
• Est. Priority Date: 12/28/2007
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Li, Jianmin, Intoccia, Alfred
• Granted Patent: US 8,123,817 B2
• Time in Patent Office: Days
• US Class Current: 606/151
• CPC Class Codes: A61F 2/0045 Support slings
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes

Abstract

According to one aspect, the present invention provides a substantially two-dimensional surgical mesh comprising a base material, a first area having a first characteristic and a second area having a second characteristic that differs from the first characteristic. The surgical mesh may further comprise a third area having a third characteristic that may be the same as or different from the first and second characteristics, and so on.

Claims

1. A substantially two-dimensional surgical mesh comprising a base material, a first area that is provided with a first material and a second area that is provided with a second material, wherein the first and second materials arc different from one another, and wherein the first and second materials are selected from (a) materials that promote a tissue response, (b) materials having bioinert properties, (c) materials that block or delay tissue ingrowth, (d) materials that reduce tissue adhesions, (e) materials that reduce tissue erosion, (f) materials that promote bonding of the mesh to adjacent tissue, (g) biodegradable materials, and (h) materials that generate distinctive color from other portion of the mesh.

2. The surgical mesh of claim 1, further comprising a third area which is provided with a third material which may be the same or different from the first material and the same or different from the second material.

3. The surgical mesh of claim 1, wherein the mesh comprises a knitted construction.

4. The surgical mesh of claim 1, wherein the mesh comprises a woven construction.

5. The surgical mesh of claim 1, wherein the mesh comprises pores greater than or equal to 5 microns in width.

6. The surgical mesh of claim 1, wherein the base material comprises a non-bioresorbable polymeric filament that comprises a polymer selected from a polyolefin, a fluoropolymer, a polyester, and combinations thereof.

7. The surgical mesh of claim 1, wherein the base material comprises a non-bioresorbable polymeric filament that comprises a polymer selected from a polypropylene, polytetrafluoroethylene, polyvinylidene fluoride, polyethylene terephthalate, and combinations thereof.

8. The surgical mesh of claim 1, wherein the base material comprises a mesh filament and wherein said first and second materials are independently (a) disposed within the interior of the mesh filament, (b) attached to the surface of the mesh filament, (c) applied as coating that at least partially surrounds the mesh filament and does not fill the pores of the mesh, (d) applied as a biostable or bioresorbable coating that at least partially surrounds the mesh filament and at least partially fills the pores of the mesh, or (e) physically woven into or physically attached to the mesh filament.

9. The surgical mesh of claim 1, wherein the first and second materials are selected from (a) a material that promotes a tissue response selected from biodegradable polymers, growth factors, and combinations thereof, (b) a material having bioinert properties selected from fluoropolymers, polyurethanes, and combinations thereof, (c) a material that temporarily blocks tissue ingrowth selected from carboxymethyl cellulose, hyaluronic acid, alginate, and combinations thereof, (d) a material that reduces tissue adhesions selected from carboxymethyl cellulose, hyaluronic acid, collagen, and combinations thereof, (e) a material that reduce tissue erosion selected from carboxymethyl cellulose, hyaluronic acid, collagen, and combinations thereof, and (f) materials that promote bonding of the mesh to adjacent tissue selected from fibrinogen.

10. The surgical mesh of claim 1, wherein the mesh comprises an elongated mesh body.

11. The surgical mesh of claim 1, wherein the mesh comprises a central mesh portion comprising an area comprising said first material and a plurality of mesh arms emanating from the central mesh portion, and wherein at least one mesh arm comprise an area comprising said second material.

12. The surgical mesh of claim 11, wherein the first material comprises a material having bioinert properties and said second material comprises a material that promotes a tissue response, a material that promotes bonding of the mesh to tissue, or a combination thereof.

13. The surgical mesh of claim 11, wherein the first material comprises a material that reduces tissue erosion and said second material comprises a material that promotes a tissue response, a material that promotes bonding of the mesh to tissue, or a combination thereof.

14. The surgical mesh of claim 11, wherein the first material comprises a biodegradable material and said second material comprises a material that promotes a tissue response, a material that promotes bonding of the mesh to tissue, or a combination thereof.

15. The surgical mesh of claim 11, wherein the first material comprises a material selected from carboxymethyl cellulose, hyaluronic acid, alginate, collagen, biodegradable polymers, growth factors and combinations thereof and said second material comprises a material selected from biodegradable polymers, growth factors, fibrinogen and combinations thereof.

16. The surgical mesh of claim 11, wherein the central mesh portion further comprises an area that does not comprise said first material.

17. The surgical mesh of claim 11, wherein said at least one mesh arm further comprises an area that does not comprise said second material.