BLOOD TREATMENT FILTER AND BLOOD TREATMENT CIRCUIT

• US 20090173685A1
• Filed: 06/15/2007
• Published: 07/09/2009
• Est. Priority Date: 06/16/2006
• Status: Abandoned Application

• Current Assignee: Terumo Kabushiki Kaisha (Terumo Corporation)
• Original Assignee: Terumo Kabushiki Kaisha (Terumo Corporation)
• Inventors: Murakoshi, Masahide, Ohkawara, Junichi, Imai, Tadashi
• Application Number:
  US12/305,076
• Publication Number:
  US 20090173685A1
• Time in Patent Office: Days
• US Class Current: 210/243
• CPC Class Codes: A61M 1/0222 and filter bypass
• CPC Class Codes: A61M 1/0231 with gas separating means, e.g. air outlet through microporous membrane or gas bag
• CPC Class Codes: A61M 1/0236 with sampling means, e.g. sample bag or sampling port
• CPC Class Codes: A61M 1/3633 Blood component filters, e.g. leukocyte filters

Abstract

A blood treatment filter which comprises a housing including an inlet and an outlet, and a filter unit for filtering blood containing erythrocytes, platelets and leukocytes as blood cell components is provided.

The filter unit comprises a main filter unit which virtually removes predetermined cell components from blood and passes the remaining blood cell components, and a pre-filter unit which is arranged at the up-stream side of the main filter and virtually does not remove blood cell components.

The pre-filter unit has a permeability rate of 70 to 90% for micro particles having an average particle size of 6 μm which are contained in a suspension and passed by gravity.

Claims

1. A blood treatment filter including,

a housing having an inlet and an outlet, and

a filter unit which is stored in the housing and filters blood containing erythrocytes, platelets, and leukocytes as blood components, wherein

the filter unit includes a main filter unit for virtually removing predetermined blood components in the blood and passing the other blood components, and a pre-filter unit which does not virtually remove the blood cell components, and

the pre-filter unit has a permeability rate of 70 to 90% for micro particles having an average particle size of 6 μ

m which are contained in a suspension and passed through by gravity.

2. The blood treatment filter according to claim 1, wherein

the main filter unit has a removal rate of 85 to 99% for first micro particles having an average particle size of 3 μ

m which are contained in the suspension containing the first micro particles and passed through by gravity.

3. The blood treatment filter according to claim 2, wherein

the suspension containing the first micro particles is passed through the main filter by gravity so that an average flow speed of the suspension is 50 mL/min.

4. The blood treatment filter according to claim 1, wherein

the suspension containing second micro particles having an average particle size of 6 μ

m is passed through the pre-filter by gravity so that an average flow speed is 50 mL/min.

5. The blood treatment filter according to claim 1, wherein

an absolute surface zeta potential value of the pre-filter is −

2.0 to +2.0 mV.

6. The blood treatment filter according to claim 1, wherein

the filter unit has a treated blood amount per unit volume of 10 to 20 mL/cm³ for the blood which is passed through by gravity.

7. The blood treatment filter according to claim 1, wherein

a volume rate between the pre-filer unit and the main filter unit is 1:

5 to 1;

20.

8. The blood treatment filter according to claim 1, wherein

the absolute surface zeta potential value of the main filter unit is −

2.0 to +2.0 mV.

9. The blood treatment filter according to claim 1, wherein

the main filter unit and the pre-filter unit are sponge-like porous membranes having a number of micro communication holes communicating one side of the membrane to the other side and a structure of fluid permeability.

10. The blood treatment filter according to claim 1, wherein

the blood is within 24 hors after blood collection from a donor.

11. The blood treatment filter according to claim 1, wherein

the main filter unit virtually removes only leukocytes from the blood, and passes erythrocytes and platelets.

12. A blood treatment circuit comprising:

the blood treatment filter according to claim 1;

a blood collecting apparatus which communicates with the inlet of the blood treatment filter and includes a primary bag for storing the collected blood; and

a blood treatment apparatus which communicates with the outlet of the blood treatment filter includes a secondary bag for collecting the remaining blood cell components which flow out from the outlet and from which the predetermined blood cell components are removed.

13. The blood treatment circuit according to claim 12, wherein the blood collecting apparatus comprises:

the primary bag;

a blood collecting needle;

a first tube of which end is connected with the primary bag and the other end is connected with the blood collecting needle; and

a second tube of which end is connected with the primary bag and the other end is connected with the inlet of the blood treatment filter.

14. The blood treatment circuit according to claim 12, wherein the blood treatment apparatus comprises:

the secondary bag;

a third tube of which end is connected with the outlet of the blood treatment filter and the other end is connected with the secondary bag;

a third bag for storing the blood cell components separated from the blood cell components stored in the secondary bag;

a forth bag in which a medical liquid is filled beforehand;

a forth tube of which end is connected with the secondary bag;

a fifth tube of which end is connected with the forth tube and the other end is connected with the third bag; and

a sixth tube of which end is connected with the forth tube and the other end is connected with the forth bag.