Wireless temperature sensing system for lyophilization processes
First Claim
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1. An apparatus, comprising:
- a stopper having an upper surface, a side surface, and a lower surface defining a unitary body that is configured to be removably secured to an open end of a flask such that contents in said flask are inhibited from escpaing;
a control unit housed within said unitary body;
a parameter sensor connected with said control unit, wherein at least a portion of said parameter sensor is housed within said unitary body; and
a transmitter connected with said control unit, wherein said control unit is configured to periodically transmit a parameter reading from said parameter sensor to a remote monitoring device with said transmitter.
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Abstract
A wireless parameter sensing system for a flask for use in lyophilization as well as a method of controlling a lyophilization process based on the sensed readings is disclosed. The wireless parameter sensing system may include a stopper adapted to be removably secured to an open end of the flask. A control unit may be positioned within an inner portion of the stopper. A parameter sensor may be connected with the control unit. A radio frequency transmitter may be connected with the control unit, wherein the control unit is operable to periodically transmit a parameter reading from the parameter sensor with the radio frequency transmitter.
62 Citations
20 Claims
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1. An apparatus, comprising:
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a stopper having an upper surface, a side surface, and a lower surface defining a unitary body that is configured to be removably secured to an open end of a flask such that contents in said flask are inhibited from escpaing; a control unit housed within said unitary body; a parameter sensor connected with said control unit, wherein at least a portion of said parameter sensor is housed within said unitary body; and a transmitter connected with said control unit, wherein said control unit is configured to periodically transmit a parameter reading from said parameter sensor to a remote monitoring device with said transmitter. - View Dependent Claims (2, 3, 4, 5, 6, 8, 9, 10, 11)
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12. An apparatus, comprising:
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a stopper having an upper surface, a side surface, and a lower surface defining a first unitary body that is configured to be removably secured to an open end of said flask such that contents in said flask are inhibited from escpaing; a housing defining a second unitary body connected to said upper surface of said first unitary body; a parameter sensor extending from said housing through said first unitary body of said stopper such that an end of said parameter sensor is exposed from said lower surface of said stopper; and a controller connected with said parameter sensor, wherein said control is positioned within said second unitary body. - View Dependent Claims (13, 14, 15, 16, 17, 18)
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19. An apparatus, comprising:
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a flask having an opening and a interior cavity defining a storage area; a stopper having an upper surface, a side surface, and a lower surface defining a unitary body that is configured to be removably secured within said opening of said flask such that contents in said flask are inhibited from escpaing; a control unit housed within said unitary body; a parameter sensor connected with said control unit, wherein at least a portion of said parameter sensor is housed within said unitary body and extends downwardly toward from said lower surface into said storage area of said flask; a transmitter connected with said control unit, wherein said control unit is configured to periodically transmit a parameter reading from said parameter sensor to a remote monitoring device with said transmitter; and a power source housed within said unitary body connected with said control unit.
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20. The apparatus of claim 20, further comprising a porous ventilation medium in said unitary body.
Specification