BIOLOGICAL AND CHEMICAL TEST MEDIA AND SYSTEM

• US 20090176312A1
• Filed: 12/03/2008
• Published: 07/09/2009
• Est. Priority Date: 12/04/2007
• Status: Abandoned Application

• Current Assignee: Sony Dadc (Sony Group Corp.)
• Original Assignee: Sony Dadc (Sony Group Corp.)
• Inventors: Selinfreund, Richard H.
• Application Number:
  US12/327,612
• Publication Number:
  US 20090176312A1
• Time in Patent Office: Days
• US Class Current: 436/164
• CPC Class Codes: B01L 2300/0806 Standardised forms, e.g. compact disc [CD] format
• CPC Class Codes: B01L 7/52 with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples amplification or hybridisation processes per se C12Q1/68; controlling sequential reactions for synthesis B01J19/0046
• CPC Class Codes: G01N 35/00069 whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk

Abstract

An apparatus and method for performing medical, biological or chemical tests in the field is Disclosed. In some embodiments, the test media comprises a special purpose optical disc which is read, after application of the test specimen and subsequent processing using commonly available CD, DVD, High Definition DVD or Blu-Ray optical disc players.

Claims

1. A test carrier for detecting analytes comprising:

an optical media having a planar read side surface and a data side surface;

a specialized test material for an analyte applied on or in at least a portion of said read side surface; and

said specialized test material comprising material which changes the state of at least one optical characteristic in response to contact with said analyte.

2. A method of detecting an analyte contained in a specimen comprising:

obtaining said specimen;

providing an optical medium incorporating a specialized test material for an analyte;

applying said specimen to said specialized test material on or in said optical medium;

reading said optical medium on optical player; and

detecting presence of said analyte compound using data read from said optical medium.

3. A method of manufacturing an optical medium comprising:

obtaining an optical medium including pre-recorded data;

printing a specialized test material on or in at least a portion of the said optical disc.

4. A disc readable by an optical disc reader comprising:

a circular substrate having an upper surface and a lower surface;

at least one test site located on said upper surface configured to receive a biological sample;

said at least one test site containing a test material that interacts with said biological sample;

said disc containing software to command processor to search said disc for said test sites and analyze characteristics at said test sites.

5. A method, using a companion diagnostic device, for assessing and modifying physiological status comprising:

obtaining a first physiologically relevant sample and delivering said sample to the companion diagnostic device for analysis;

analyzing said first physiologically relevant sample;

evaluating the physiological significance of one or more assay results produced by said companion diagnostic device, each of said assay results representing a valid, quantitative measurement of a physiological marker relevant to physiological status;

engaging in an activity that may affect the physiological status;

obtaining a second physiologically relevant sample and delivering said second sample to the companion diagnostic device for analysis;

analyzing said second physiologically relevant sample;

again evaluating the physiological significance of one or more assay results produced by the companion diagnostic device upon analysis of the sample, each of said assay results representing a valid, quantitative measurement of a physiological marker appropriate for assessing the physiological status;

assessing the change in physiological status by comparing the results of the analysis of said first sample with analysis of said second sample; and

modifying said activity based upon the change in physiological status.

6. The method of claim 5 wherein the physiological status is diabetic fitness.

7. The method of claim 5 wherein the said sample is saliva.

8. The method of claim 5 wherein the said sample is urine.

9. The method of claim 5 wherein the said sample is fecal matter.

10. The method of claim 5 wherein the said sample is exhalate.

11. The method of claim 5 wherein said physiological marker is insulin.

12. The method of claim 5 wherein said physiological marker is selected from the group consisting of a catecholamine, a triglyceride, a carbohydrate, a gene, salivary pH, a ketone, and an electrolyte.

13. The method of claim 5 wherein said physiological marker is the respiratory quotient.

14. The method of claim 5 wherein said samples are sent to a remote testing site for analysis and the results are communicated back.

15. The method of claim 5 wherein the companion diagnostic device comprises a plurality of bands impregnated on a test strip, wherein each test strip comprises a reaction system selective to essentially one appropriate physiological marker, wherein each reaction system produces a result that is quantitatively associated with said appropriate physiological marker.

16. The method of claim 5 wherein said assay results are displayed in table form.

17. An apparatus facilitating the reaction of an analyte with a test material on a digitally-readable medium to yield a detectable signal readable by a reader of the digitally readable medium, said apparatus comprising:

a sealed housing encompassing a void, said housing void structurally dimensioned to enclose said digitally-readable medium;

a entrance port providing communication between the environment ambient to said enclosed housing and said void of said housing, said entrance port operatively configured to permit said digitally-readable medium to pass through said entrance port into said void of said housing, and to keep said housing sealed against the ambient environment outside of said entrance port;

at least one fluid pump module having an a fluid reservoir exterior to said housing, and a conduit communicating with said void of said housing;

a processor operatively coupled with said housing, said processor controlling said at least one fluid pump module to dispense fluid from said fluid reservoir into said void of said housing;

at least one detector configured to detect when said void encompasses said digitally-readable medium, and to detect conditions within said void of said housing;

an instruction set configured to control said processor to time dispensing of said fluid into said void of said housing according to said test material on said digitally-readable medium.

18. The apparatus of claim 17 wherein said digitally-readable medium comprises an optical disc selected from the group consisting of:

a Blu-Ray, HD, DVD, CD disc.