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CHRONICALLY IMPLANTABLE HYBRID CANNULA-MICROELECTRODE SYSTEM FOR CONTINUOUS MONITORING ELECTROPHYSIOLOGICAL SIGNALS DURING INFUSION OF A CHEMICAL OR PHARMACEUTICAL AGENT

  • US 20090187159A1
  • Filed: 01/17/2008
  • Published: 07/23/2009
  • Est. Priority Date: 01/17/2008
  • Status: Abandoned Application
First Claim
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1. An apparatus for sensing an electrophysiological signal in a target tissue and for infusing an agent into the target tissue comprising:

  • a body;

    a cannula mounted on the body; and

    a sensing microelectrode, characterized by having an impedance of approximately 0.2-2 MΩ

    at sensed frequencies when implanted into the target tissue and/or an exposed electrically conductive surface area of approximately ten to several thousand square micrometers, in proximity to the cannula and mounted on the body so that the agent supplied to the cannula is provided to the proximity of the target tissue into which at least one electrophysiological microelectrode is electrically coupled.

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