Medicaments
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Abstract
This invention relates to aerosol formulations of use for the administration of medicaments by inhalation, in particular a pharmaceutical aerosol formulation which comprises particulate salbutamol and physiologically acceptable salts and solvates thereof and a fluorocarbon or hydrogen-containing chlorofluorocarbon propellant, which formulation is substantially free of surfactant. A method of treating respiratory disorders which comprises administration by inhalation of an effective amount of a pharmaceutical aerosol formulation as defined is also described.
54 Citations
23 Claims
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1-17. -17. (canceled)
- 18. A pharmaceutical aerosol formulation comprising particulate medicament which is fluticasone propionate or a physiologically acceptable solvate thereof, and 1,1,1,2,3,3,3-heptafluoro-n-propane as propellant, which formulation is essentially free of surfactant and free of chlorofluorocarbons, the particulate medicament being present in an amount from 0.005% to 5% w/w relative to the total weight of the formulation and having a particle size not less than 100 microns.
Specification