DEVICE FOR DETERMINING THE QUALITY AND SOLIDNESS OF THE VASCULAR WALL

• US 20090191615A1
• Filed: 01/23/2009
• Published: 07/30/2009
• Est. Priority Date: 01/25/2008
• Status: Active Grant

• Current Assignee: Jaroslav Benedik
• Original Assignee: Jaroslav Benedik
• Inventors: Benedik, Jaroslav
• Granted Patent: US 7,997,146 B2
• Time in Patent Office: Days
• US Class Current: 435/287.1
• CPC Class Codes: A61B 5/0055 by applying suction
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: G01N 2203/0282 Two dimensional, e.g. tapes, webs, sheets, strips, disks or membranes
• CPC Class Codes: G01N 3/24 by applying steady shearing forces G01N3/26, G01N3/28 take precedence
• CPC Class Codes: G01N 33/4833 of solid biological material, e.g. tissue samples, cell cultures tissue in vivo A61B5/00; cell suspensions G01N33/48735

Abstract

A device for determining the quality and solidness of the vascular wall is provided for testing tissue samples and includes opposed first and second fixation plates. The fixation plates are connectable to an air pump or other source of vacuum for fixing the tissue sample in position. The device is connectable to a detector such as a meter, gauge, or printing device capable of displaying or producing an image or display corresponding to the value of a force required to disrupt or break the internal links between individual layers of the vascular wall. The fixation plates are movable relative to one another and may be abducted by abductors connecting the plates or by rotational movement of one fixation plate relative to the other by a shaft or other rotational mechanism.

Claims

1. A device for determining the quality and solidness of the vascular wall which can be used to determine the mutual cohesiveness of individual layers of the vascular wall by a destructive method on tissue samples comprising:

first and second fixation plates which are movable one relative to another and configured for receiving and fixing a tissue sample therebetween; and

a connector for operatively connecting at least one of the fixation plates to a detector for providing a signal for measuring and/or recording a value corresponding to the solidness of the tissue sample with mutual abduction and/or rotation of the fixation plates.

2. The device for determining the quality and solidness of the vascular wall according to claim 1, including an abductor for linearly abducting the one of the first and second fixation plates relative to the other.

3. The device for determining the quality and solidness of the vascular wall according to claim 1 including a longitudinal joint connecting the first and second fixation plates and an abductor for abducting one of the first and second fixation plates relative to the other, and for determining their relative angular abduction.

4. The device for determining the quality and solidness of the vascular wall according to claim 1 including a shaft operatively connected to one of the fixation plates for applying a torsional force for moving the one of the fixation plates relative to the other fixation plate.

5. The device for determining the quality and solidness of the vascular wall according to claim 4, wherein the shaft is firmly fixed to the one fixation plate and passes through the one fixation plate and through the tissue sample and is received in a bearing mounted on the other fixation plate.

6. The device for determining the quality and solidness of the vascular wall according to claim 1, wherein the first and second fixation plates are each provided with respective opposing walls, and wherein the wall of the first fixation plate includes a blade of a closed geometric shape and wherein the wall of the second fixation plate is provided with a groove complementally shaped and sized with the blade, and wherein the blade and groove determine a standard size of a tissue sample having a surface area adapted to the shape and size of the blade and groove which tissue sample is to be tested by the device.

7. The device for determining the quality and solidness of the vascular wall according to claim 1, wherein the first and second fixation plates are each provided with respective opposing walls having holes, each of said first and second fixation plates further including outlets operatively connected the holes and adapted for connection to a source of negative fluid pressure for fixing the tissue sample to the first and second fixation plates.

8. The device for determining the quality and solidness of the vascular wall according to claim 2, wherein the first and second fixation plates are each provided with respective opposing walls, and wherein the wall of the first fixation plate includes a blade of a closed geometric shape and wherein the wall of the second fixation plate is provided with a groove complementally shaped and sized with the blade, and wherein the blade and groove determine a standard size of a tissue sample having a surface area adapted to the shape and size of the blade and groove which tissue sample is to be tested by the device.

9. The device for determining the quality and solidness of the vascular wall according to claim 3, wherein the first and second fixation plates are each provided with respective opposing walls, and wherein the wall of the first fixation plate includes a blade of a closed geometric shape and wherein the wall of the second fixation plate is provided with a groove complementally shaped and sized with the blade, and wherein the blade and groove determine a standard size of a tissue sample having a surface area adapted to the shape and size of the blade and groove which tissue sample is to be tested by the device.

10. The device for determining the quality and solidness of the vascular wall according to claim 4, wherein the first and second fixation plates are each provided with respective opposing walls, and wherein the wall of the first fixation plate includes a blade of a closed geometric shape and wherein the wall of the second fixation plate is provided with a groove complementally shaped and sized with the blade, and wherein the blade and groove determine a standard size of a tissue sample having a surface area adapted to the shape and size of the blade and groove which tissue sample is to be tested by the device.

11. The device for determining the quality and solidness of the vascular wall according to claim 2, wherein the first and second fixation plates are each provided with respective opposing walls having holes, each of said first and second fixation plates further including outlets operatively connected the holes and adapted for connection to a source of negative fluid pressure for fixing the tissue sample to the first and second fixation plates.

12. The device for determining the quality and solidness of the vascular wall according to claim 3, wherein the first and second fixation plates are each provided with respective opposing walls having holes, each of said first and second fixation plates further including outlets operatively connected the holes and adapted for connection to a source of negative fluid pressure for fixing the tissue sample to the first and second fixation plates.

13. The device for determining the quality and solidness of the vascular wall according to claim 4, wherein the first and second fixation plates are each provided with respective opposing walls having holes, each of said first and second fixation plates further including outlets operatively connected the holes and adapted for connection to a source of negative fluid pressure for fixing the tissue sample to the first and second fixation plates.

14. The device for determining the quality and solidness of the vascular wall according to claim 6, wherein the first and second fixation plates are each provided with respective opposing walls having holes, each of said first and second fixation plates further including outlets operatively connected the holes and adapted for connection to a source of negative fluid pressure for fixing the tissue sample to the first and second fixation plates.

15. A device for determining the quality and solidness of the vascular wall which can be used to determine the mutual cohesiveness of individual layers of the vascular wall by a destructive method comprising:

first and second mutually flexible opposite fixation plates, one being movable relative to the other of random shape, and adapted to receive a tissue sample between and fixed to them, the device being connected to a detector for measuring and recording a value corresponding to the solidness of the tissue sample with mutual abduction and/or rotation of the fixation plates.

16. The device for determining the quality and solidness of the vascular wall according to claim 15, wherein the fixation plates are capable of being abducted from each other linearly with the aid of an abductor.

17. The device for determining the quality and solidness of the vascular wall according to claim 15, wherein the fixation plates are connected by a longitudinal joint for determining their angular abduction with the aid of an abductor.

18. The device for determining the quality and solidness of the vascular wall according to claim 15, including a shaft for moving the fixation plates against each other rotationally with the aid of torsional force, said first fixation plate being positioned on top of the second fixation plate, said shaft being firmly fixed in the top fixation plate and passing through the top fixation plate, and said shaft also passing through the tissue sample to be tested and received in a slide bearing in the bottom fixation plate.

19. The device for determining the quality and solidness of the vascular wall according to claim 15, wherein each of the first and second fixation plates include a wall, said wall of the first fixation plate being opposite to the wall of the second fixation plate, and wherein the opposite walls of the fixation plates are equipped with a blade of a closed geometric shape in one of the walls and a groove in the other of the walls, said groove having a shape and size corresponding to the blade, for determining the standardised size of the tissue sample to be tested, the tissue sample having a surface area which is adapted to the shape of the blade and groove.

20. The device for determining the quality and solidness of the vascular wall according to claim 15, wherein the first and second fixation plates have inner areas which are equipped with holes, and wherein the holes are interconnected with outlets connected to an air pump for creating negative pressure for fixing the tissue sample to the fixation plates.