CHARACTERIZATION OF VULNERABLE PLAQUE USING DYNAMIC ANALYSIS
First Claim
Patent Images
1. An apparatus for a characterization of arterial plaque comprising:
- an imaging system providing image data distinguishing plaque from at least a portion of a supporting arterial wall;
an electronic computer executing a stored program and receiving the image data to;
(1) isolate movement of the plaque from movement of the supporting arterial wall under a periodic force of pulsatile blood flow;
(2) analyze the movement of the plaque to characterize a risk of the plaque rupturing to produce harmful embolisms; and
(3) output an indication of the risk.
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Abstract
Arterial plaques are evaluated by determining their deformation under the periodic pulsatile force of blood flow. A relationship between plaque deformation and rupture risk is established by measurement of a relationship between deformation and cognitive decline in a sample population. The measured parameters include the maximum accumulated axial strain, maximum lateral displacement and maximum shear strains in soft vulnerable plaques.
26 Citations
25 Claims
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1. An apparatus for a characterization of arterial plaque comprising:
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an imaging system providing image data distinguishing plaque from at least a portion of a supporting arterial wall; an electronic computer executing a stored program and receiving the image data to; (1) isolate movement of the plaque from movement of the supporting arterial wall under a periodic force of pulsatile blood flow; (2) analyze the movement of the plaque to characterize a risk of the plaque rupturing to produce harmful embolisms; and (3) output an indication of the risk. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method of characterizing of arterial plaque comprising:
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(a) collecting a series of time images distinguishing plaque and at least a portion of a supporting arterial wall; (b) using an electronic computer executing a stored program and receiving the images to; (1) isolate movement of the plaque from movement of the supporting arterial wall under a periodic force of pulsatile blood flow; (2) analyze the movement of the plaque to characterize a risk of the plaque rupturing to produce dangerous embolisms; and (3) output an indication of the risk. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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Specification