Rest phase heart pacing

• US 20090204165A1
• Filed: 01/23/2009
• Published: 08/13/2009
• Est. Priority Date: 01/29/2008
• Status: Active Grant

• Current Assignee: Inovise Medical, Inc.
• Original Assignee: Inovise Medical, Inc.
• Inventors: Bauer, Peter T.
• Granted Patent: US 8,412,323 B2
• Time in Patent Office: Days
• US Class Current: 607/18
• CPC Class Codes: A61N 1/36578 controlled by mechanical motion of the heart wall, e.g. measured by an accelerometer or microphone
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters

Abstract

A computer method, employable during an at-rest period of a pacemaker patient, for controlling the operation of the pacemaker so as maximally to support the patient'"'"'s hemodynamic behavior in a context involving inhibiting fluid overload. The method involves (a) collecting simultaneously occurring ECG and heart-sound information, (b) processing the collected information to obtain at least S3 data, and in certain instances also EMAT and/or % LVST data, (c) utilizing such obtained data, and during the at-rest period, applying (a) pacing rate, (b) pacing intensity, (c) atrio-ventricular delay, and (d) inter-ventricular delay control to the pacemaker. Processing involves (a) calculating from the obtained data an actual, real-time, acoustic cardiographic therapy (AC) value which is to be employed in relation to controlling pacemaker activity, and (b) comparing the actual AC value to a pre-established, related, rest-period-associated, reference AC value to detect differences therebetween, with the utilizing and applying steps being implemented so as to minimize such differences.

Claims

1. A computer-performed method, employable during an at-rest period of a pacemaker patient having heart failure and being at risk for fluid overload, for adjusting and controlling the operation of the patient'"'"'s pacemaker so as to effect pacing in a manner maximally supporting the patient'"'"'s hemodynamic behavior in a context involving inhibiting fluid overload, said method comprising

collecting, effectively in a continuum during such a period, simultaneously occurring ECG and heart-sound continuum information,

computer-processing the collected continuum information to obtain at least S3 data, and

effectively utilizing such at least S3 data, and during the mentioned at-rest period, appropriately applying at least one of (a) pacing rate, (b) pacing intensity, (c) atrio-ventricular delay, and (d) inter-ventricular delay control to the pacemaker.

2. The method of claim 1, wherein said computer-processing involves (a) calculating, based on the S3 data obtained from the collected continuum data, an actual, real-time, acoustic cardiographic therapy (AC) value which is to be employed in relation to said adjusting and controlling, and (b) comparing such calculated, actual AC value to a pre-established, related, rest-period-associated, reference AC value to detect differences therebetween, and said utilizing and applying are conducted so as to minimize such differences.

3. A computer-performed method, employable during an at-rest period of a pacemaker patient having heart failure and being at risk for fluid overload, for adjusting and controlling the operation of the patient'"'"'s pacemaker so as to effect pacing in a manner maximally supporting the patient'"'"'s hemodynamic behavior in a context involving inhibiting fluid overload, said method comprising

collecting, effectively in a continuum, during such a period simultaneously occurring ECG and heart-sound continuum information,

computer-processing the collected continuum information to obtain S3 data and at least one of EMAT and % LVST data, and

effectively utilizing such computer-processed data, and during the mentioned at-rest period, appropriately applying at least one of (a) pacing rate, (b) pacing intensity, (c) atrio-ventricular delay, and (d) inter-ventricular delay control to the pacemaker.

4. The method of claim 3, wherein said computer-processing involves (a) calculating, based on the S3 data, and on the at least one of the EMAT and % LVST data, obtained from the collected continuum data, an actual, real-time, acoustic cardiographic therapy (AC) value which is to be employed in relation to said adjusting and controlling, and (b) comparing such calculated, actual AC value to a pre-established, related, rest-period-associated, reference AC value to detect differences therebetween, and said utilizing and applying are conducted so as to minimize such differences.