KIT FOR ADMINSTERING A THERAPEUTIC AGENT INTO TISSUE

• US 20090209902A1
• Filed: 04/28/2009
• Published: 08/20/2009
• Est. Priority Date: 10/06/2003
• Status: Abandoned Application

• Current Assignee: Active O, LLC, Ceramatec, Inc. (Trelleborg AB)
• Original Assignee: Ceramatec, Inc. (Trelleborg AB)
• Inventors: Murphy, Kieran P., Muto, Mario
• Application Number:
  US12/431,062
• Publication Number:
  US 20090209902A1
• Time in Patent Office: Days
• US Class Current: 604/25
• CPC Class Codes: A61B 17/3478 Endoscopic needles, e.g. for infusion biopsy needles A61B10/0233; catheters with injection needles A61M25/0067
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 33/00 Medicinal preparations containing inorganic active ingredients
• CPC Class Codes: A61K 33/40 Peroxides
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61M 2005/3114 Filling or refilling
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 2202/0208 Oxygen
• CPC Class Codes: A61M 2202/0216 Ozone
• CPC Class Codes: A61M 2210/1003 Spinal column
• CPC Class Codes: A61M 25/065 Guide needles
• CPC Class Codes: A61M 5/28 Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: A61P 19/02 for joint disorders, e.g. arthritis, arthrosis
• CPC Class Codes: A61P 25/04 Centrally acting analgesics, e.g. opioids

Abstract

An apparatus for administering a therapeutic agent is provided. The apparatus, in an embodiment, includes an ozone generator connected to a scavenger and an ozone administrator via network of tubing and valves. When activated and the valves placed in the proper position, the ozone generator will fill the ozone administrator with ozone. The ozone generator can then be turned off and the valves moved so that the administrator can be disconnected from the remainder of the apparatus. The administrator is typically in the form of a syringe and needle. Once the syringe and needle is filled with ozone, the needle can be inserted into a tissue and the ozone expressed therefrom into the tissue. Various other apparatuses and methods are also contemplated.

Claims

1. A kit of parts for use in administering a therapeutic agent comprising:

a disinfectant;

a drape;

a skin preparation material;

a local anesthetic;

at least one syringe;

at least one of a short and a long needle for use with said syringe;

a gantry drape for shielding a patient in an imaging device;

a radiolucent needle holder;

a therapeutic agent generator;

a post-operative dressing for skin closure; and

at least one adhesive bandage.

2. The kit of claim 1, further comprising a therapeutic agent administrator for administering therapeutic agent generated by the therapeutic agent generator.

3. The kit of claim 2, further comprising a scavenger for capturing excess therapeutic agent.

4. The kit of claim 3, wherein the therapeutic agent administrator, the therapeutic agent generator, and the scavenger are in operable communication with each other.

5. The kit of claim 4, wherein at least one valve is positioned between the therapeutic agent generator and the therapeutic agent administrator, such that by operation of the at least one valve, the administrator can be filled and excess therapeutic agent can be captured by the scavenger.

6. The kit of claim 1, wherein said therapeutic agent comprises ozone.

7. The kit of claim 1, wherein said therapeutic agent comprises oxygen.

8. The kit of claim 1, wherein said generator comprises a medical ozone generator.

9. The kit of claim 6, wherein said ozone comprises gaseous medical ozone comprising a ratio of ozone (O₃) to oxygen (O₂).

10. The kit of claim 9, wherein said ratio of ozone to oxygen comprises about 1 μ

g/ml.

11. The kit of claim 9, wherein said ratio of ozone to oxygen comprises about 10 μ

g/ml.

12. The kit of claim 9, wherein said ratio of ozone to oxygen comprises about 20 μ

g/ml.

13. The kit of claim 9, wherein said ratio of ozone to oxygen comprises 30 μ

g/ml.

14. The kit of claim 9, wherein said ratio of ozone to oxygen comprises about 40 μ

g/ml.

15. The kit of claim 9, wherein said ratio of ozone to oxygen comprises about 50 μ

g/ml.

16. The kit of claim 9, wherein said ratio of ozone in micrograms to oxygen in milliliters is between about 1 μ

g/ml and about 90 μ

g/ml.

17. The kit of claim 16, wherein said ratio of ozone in micrograms to oxygen in milliliters is between about 10 μ

g/ml and about 80 μ

g/ml.

18. The kit of claim 17, wherein said ratio of ozone in micrograms to oxygen in milliliters is between about 20 μ

g/ml and about 70 μ

g/ml.

19. The kit of claim 18, wherein said ratio of ozone in micrograms to oxygen in milliliters is between about 10 μ

g/ml and about 34 μ

g/ml.

20. The kit of claim 19, wherein said ratio of ozone in micrograms to oxygen in milliliters is between about 27 μ

g/ml to about 28 μ

g/ml.

21. The kit of claim 4, wherein two valves control the flow of therapeutic agent between the therapeutic agent generator, the scavenger and the therapeutic agent administrator.

22. The kit of claim 21, wherein a combination of closing and opening each of the valves allows passage of therapeutic agent between the therapeutic agent generator and the therapeutic administrator without allowing therapeutic agent to access the scavenger.

23. The kit of claim 21, wherein a combination of closing and opening each of the valves allows passage of therapeutic agent between the therapeutic agent in the therapeutic administrator or between the therapeutic agent generator and the therapeutic administrator to access the scavenger.

24. The kit of claim 21, wherein when said valves are in a first position said generator communicates with said administrator for filling said administrator with said agent and when said valves are in a second position said administrator retains said agent therein upon disconnection from said generator and said scavenger captures any excess agent intermediate said administrator and said generator.

25. The kit of claim 2, wherein the syringe comprises the administrator and the generator.

26. The kit of claim 25, wherein the syringe comprises:

a barrel for holding said agent;

a plunger for insertion into a first end of said barrel and expressing said agent from a second end of said barrel;

a power supply integrally mounted coaxially with said plunger;

a therapeutic agent generator integrally mounted coaxially with said plunger and in communication with said barrel through a channel in said plunger, said generator connected to said power supply and mounted coaxially with said plunger;

a switch connected to said power supply such that when said switch is activated said therapeutic agent generator generates said therapeutic agent and fills said barrel therewith.

27. The kit of claim 26, wherein said agent comprises ozone.

28. The kit of claim 27, wherein said generator comprises a medical ozone generator.

29. The kit of claim 28, wherein said ozone comprises gaseous medical ozone comprising a ratio of ozone (O₃) to oxygen (O₂).

30. The kit of claim 29, wherein said ratio of ozone to oxygen comprises about 1 μ

g/ml.

31. The kit of claim 29, wherein said ratio of ozone to oxygen comprises about 10 μ

g/ml.

32. The kit of claim 29, wherein said ratio of ozone to oxygen comprises about 20 μ

g/ml.

33. The kit of claim 29, wherein said ratio of ozone to oxygen comprises about 30 μ

g/ml.

34. The kit of claim 29, wherein said ratio of ozone to oxygen comprises about 40 μ

g/ml.

35. The kit of claim 29, wherein said ratio of ozone to oxygen comprises about 50 μ

g/ml.

36. The kit of claim 29, wherein said ratio of ozone in micrograms to oxygen in milliliters is between about 1 μ

g/ml and about 90 μ

g/ml.

37. The kit of claim 35, wherein said ratio of ozone in micrograms to oxygen in milliliters is between about 10 μ

g/ml and about 80 μ

g/ml.

38. The kit of claim 36, wherein said ratio of ozone in micrograms to oxygen in milliliters is between about 20 μ

g/ml and about 70 μ

g/ml.

39. The kit of claim 37, wherein said ratio of ozone in micrograms to oxygen in milliliters is between about 10 μ

g/ml and about 34 μ

g/ml.

40. The kit of claim 38, wherein said ratio of ozone in micrograms to oxygen in milliliters is between about 27 μ

g/ml to about 28 μ

g/ml.