DRUG DELIVERY PATCH

• US 20090214625A1
• Filed: 07/18/2006
• Published: 08/27/2009
• Est. Priority Date: 07/15/2005
• Status: Abandoned Application

• Current Assignee: TTI Ellebeau, Inc. (Ease Asset Management Ltd.)
• Original Assignee: TTI Ellebeau, Inc. (Ease Asset Management Ltd.)
• Inventors: Nakayama, Mizuo, Matsumura, Akihiko, Matsumura, Takehiko, Akiyama, Hidero
• Application Number:
  US11/995,796
• Publication Number:
  US 20090214625A1
• Time in Patent Office: Days
• US Class Current: 424/449
• CPC Class Codes: A61F 13/0213 the fluid retention member being a layer of hydrocolloid, gel forming material
• CPC Class Codes: A61K 9/0009 involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis microelectromechanical systems A61K9/0097
• CPC Class Codes: A61K 9/703 characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
• CPC Class Codes: A61K 9/7038 Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
• CPC Class Codes: A61N 1/30 Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
• CPC Class Codes: A61P 43/00 Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

The site to which a patch was stuck may be identified even after the patch is removed.

A patch for drug delivery includes a drug holding portion and a backing layer. The patch further includes a marker capable of indicating a site to which the patch was stuck even after the patch is removed therefrom.

Claims

1. A patch for introducing a drug through a biological interface, comprising:

a drug holding portion configured to hold the drug;

a backing layer adjacent a surface of the drug holding portion; and

a marker configured to indicate a site of the biological interface to which the patch was stuck after the patch is removed from the site.

2. The patch of claim 1, wherein the marker comprises a separable portion of the backing layer or the drug holding portion, and is configured to remain on the biological interface after the patch is removed from the site.

3. The patch of claim 1, wherein the marker comprises a dye or an ink.

4. The patch of claim 1, further comprising:

at least one electrode connected to an electric power source to introduce the drug by iontophoresis.

5. The patch of claim 1, further comprising:

an electric power source; and

at least one electrode electrically coupled to the electric power source to iontophoretically deliver the drug.

6. The patch of claim 1, wherein the drug holding portion is a hydrogel.

7. The patch of claim 1, wherein the marker does not chemically react with the drug.

8. The patch of claim 1, wherein the marker is visually discernable when illuminated by white light.

9. The patch of claim 1, wherein the marker is visually discernable only when illuminated by ultraviolet light.

10. The patch of claim 1, wherein the marker is a food dye.

11. The patch of claim 1, wherein the marker is an ink.

12. The patch of claim 1, wherein the marker is luciferin.

13. The patch of claim 1, wherein the marker is odorous.

14. The patch of claim 1, wherein the marker is flavored.