Methods for the Treatment of ADHD and Related Disorders
First Claim
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1. A method for treating ADHD or a related behavioral disorder in a subject comprising:
- (a) selecting a subject having ADHD or a related behavioral disorder; and
(b) administering to the subject a non-hormonal organic cation 3 (hOCT3) inhibitor in an amount sufficient to ameliorate the symptoms of said disorder.
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Abstract
The invention features methods, compositions, and kits for the treatment of attention deficit hyperactivity disorder and related behavioral disorders by administering an organic cation 3 (hOCT3) inhibitor.
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Citations
30 Claims
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1. A method for treating ADHD or a related behavioral disorder in a subject comprising:
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(a) selecting a subject having ADHD or a related behavioral disorder; and (b) administering to the subject a non-hormonal organic cation 3 (hOCT3) inhibitor in an amount sufficient to ameliorate the symptoms of said disorder. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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- 13. A composition comprising an organic cation 3 (hOCT3) inhibitor and second agent selected from atomoxetine, a direct or indirect dopamine agonist, a 5HT1A agonist, an alpha-2 agonist or antagonist, or a cholinesterase inhibitor in amounts that together are sufficient to treat ADHD or a related behavioral disorder when administered to a patient.
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21. A kit, comprising:
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(i) a composition comprising an organic cation 3 (hOCT3) inhibitor; and (ii) instructions for administering said composition to a patient diagnosed with ADHD or a related behavioral disorder. - View Dependent Claims (23)
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22. A kit, comprising:
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(i) an organic cation 3 (hOCT3) inhibitor; (ii) a second agent selected from a norepinephrine uptake 1 inhibitor, a direct or indirect dopamine agonist, a 5HT1A agonist, an alpha-2 agonist or antagonist, or a cholinesterase inhibitor; and (iii) instructions for administering said organic cation 3 (hOCT3) inhibitor and said second agent to a patient diagnosed with ADHD or a related behavioral disorder. - View Dependent Claims (24, 25, 26, 27, 28, 29, 30)
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Specification