Apparatus and methods for making, storing, and administering freeze-dried materials such as freeze-dried plasma

• US 20090223080A1
• Filed: 02/13/2009
• Published: 09/10/2009
• Est. Priority Date: 03/19/2007
• Status: Abandoned Application

• Current Assignee: Hemcon Life Sciences, Inc.
• Original Assignee: Hemcon Medical Technologies Inc. (Tricol International Group Ltd.)
• Inventors: McCarthy, Simon J., Buckley, Lisa A.
• Application Number:
  US12/378,470
• Publication Number:
  US 20090223080A1
• Time in Patent Office: Days
• US Class Current: 34/284
• CPC Class Codes: A61B 50/10 Furniture specially adapted for surgical or diagnostic appliances or instruments
• CPC Class Codes: A61B 50/13 Trolleys, e.g. carts
• CPC Class Codes: A61B 50/30 Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments for wound clamps A61B17/10; for ligaturing clips A61B17/122; packages or dispensers for surgical gloves or finger-stalls A61B42/40
• CPC Class Codes: A61B 90/96 using barcodes
• CPC Class Codes: A61J 1/10 Bag-type containers
• CPC Class Codes: A61J 1/1475 Inlet or outlet ports
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2013 having two piercing ends
• CPC Class Codes: A61J 1/2027 having frangible parts
• CPC Class Codes: A61J 1/2037 having valve means
• CPC Class Codes: A61J 1/2093 Containers having several compartments for products to be mixed
• CPC Class Codes: A61M 2039/1061 Break-apart tubing connectors or couplings

Abstract

A method for preparing and a system containing freeze-dried plasma that will be reconstituted. Ascorbic acid is incorporated into the freeze-dried plasma prior to the plasma being reconstituted.

Claims

1. A method of freeze-drying a plasma comprising the steps of:

providing a source of plasma,

adding ascorbic acid to the plasma,

transferring the plasma from the source into a receptacle; and

freeze-drying the plasma within the receptacle.

2. A method according to claim 1

wherein the ascorbic acid is added to the plasma after transferring the plasma to the receptacle.

3. A method according to claim 1, wherein the concentration of ascorbic acid is about 15 mMol.

5. The method of claim 1,

wherein ascorbic acid is added to the reconstitution fluid.

6. The method of claim 1,

wherein ascorbic acid is added to the source of plasma prior to freeze-drying the source of plasma.

4. A method comprising the steps of:

providing a source of plasma,

freeze-drying the source of plasma;

providing a reconstitution fluid;

reconstituting the freeze dried plasma material with the reconstitution fluid; and

adding ascorbic acid to the freeze-dried plasma material prior to the step of reconstituting.

7. A system comprising:

a flexible container including first chamber holding a freeze-dried material in a dry state, a second chamber holds a reconstituting liquid for the freeze-dried material, and an ascorbic acid material, the flexible container including an interior sealing wall sized and configured to form a barrier between the first chamber and the second chamber preventing contact between the freeze-dried material and the reconstituting liquid.

8. The system of claim 7, wherein the ascorbic acid is a liquid within the second chamber of the container.

9. The system of claim 7, where the ascorbic acid is within the first chamber in a freeze-dried state.