Biosensor and method

• US 20090223834A1
• Filed: 05/15/2009
• Published: 09/10/2009
• Est. Priority Date: 07/31/2001
• Status: Abandoned Application

• Current Assignee: Nova Biomedical Corporation (Nova Chemicals)
• Original Assignee: Nova Biomedical Corporation (Nova Chemicals)
• Inventors: Young, Chung Chang, Cai, Xiaohua, Winarta, Handani
• Application Number:
  US12/466,767
• Publication Number:
  US 20090223834A1
• Time in Patent Office: Days
• US Class Current: 205/777.500
• CPC Class Codes: C12Q 1/004 mediator-assisted
• CPC Class Codes: C12Q 1/006 for glucose
• CPC Class Codes: C12Q 1/26 involving oxidoreductase
• CPC Class Codes: C12Q 1/28 involving peroxidase
• CPC Class Codes: C12Q 1/34 involving hydrolase
• CPC Class Codes: Y10T 29/49002 Electrical device making

Abstract

A method of compensating for the presence of hematocrit in a blood sample when measuring a blood analyte using a disposable sensor strip. The method includes disposing a blood sample onto a working electrode and a reference electrode of the disposable sensor strip to obtain a concentration of an analyte in the blood sample, measuring a resistance value of the blood sample between the reference electrode and the working electrode, and calculating a corrected concentration of the analyte using the resistance value and a hematocrit equation to correct for the presence of hematocrit in the blood sample.

Claims

1. A method of compensating for the presence of hematocrit in a blood sample when measuring a blood analyte using a disposable sensor strip, the method comprising:

disposing a blood sample onto a working electrode and a reference electrode of the disposable sensor strip to obtain a concentration of an analyte in the blood sample;

measuring a resistance value of the blood sample between the reference electrode and the working electrode; and

calculating a corrected concentration of the analyte using the resistance value and a hematocrit equation to correct for the presence of hematocrit in the blood sample.

2. The method of claim 1 further comprising:

applying a potential between the reference electrode and the working electrode which contains an enzyme that is a substrate of the blood analyte; and

measuring a current generated between the working electrode and the reference electrode and correlating the current to a concentration of the analyte in said the sample.

3. The method of claim 1 further comprising applying the resistance value to a first equation and determining the hematocrit level of the blood sample.