METHODS OF DETERMINING PRE OR POST MEAL TIME SLOTS OR INTERVALS IN DIABETES MANAGEMENT

• US 20090240127A1
• Filed: 03/20/2008
• Published: 09/24/2009
• Est. Priority Date: 03/20/2008
• Status: Abandoned Application

• Current Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Original Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Inventors: RAY, Pinaki
• Application Number:
  US12/052,639
• Publication Number:
  US 20090240127A1
• Time in Patent Office: Days
• US Class Current: 600/365
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/63 for local operation

Abstract

A diabetes management system or process is provided herein that may be used to analyze and recognize patterns for a large number of blood glucose concentration measurements and other physiological parameters related to the glycemia of a patient. In particular, a method of monitoring glycemia in a patient may include storing a patient'"'"'s data on a suitable device, such as, for example, a blood glucose meter. The patient'"'"'s data may include blood glucose concentration measurements. The diabetes management system or process may be installed on, but is not limited to, a personal computer, an insulin pen, an insulin pump, or a glucose meter. The diabetes management system or process may identify a plurality of pattern types from the data including a testing/dosing pattern, a hypoglycemic pattern, a hyperglycemic pattern, a blood glucose variability pattern, and a comparative pattern. After identifying a particular pattern with the data management system or process, a warning message may be displayed on a screen of a personal computer or a glucose meter. Other messages can also be provided to ensure compliance of any prescribed diabetes regiments or to guide the patient in managing the patient'"'"'s diabetes.

Claims

1. A method of determining post meal time intervals for a diabetes patient, the method comprising:

obtaining a plurality of blood glucose concentration measurements from the patient;

calculating a median glucose concentration for blood glucose concentration measurements performed during a first time slot;

performing a glucose concentration measurement during a second time slot subsequent to said first time slot; and

indicating that said glucose concentration tested during said second time slot may be flagged as post-meal if said glucose concentration measurement during said second time slot is greater than said median glucose concentration by a pre-determined threshold.

3. The method of claim 1, wherein said pre-determined threshold is about 50 milligrams per deciliter.

7. The method of one of claims 1 or 4, further comprising, performing a plurality of glucose measurements over a time interval of greater than about thirty days.

8. The method of one of claims 1 or 4, further comprising, performing a plurality of glucose measurements at a rate greater than about four times a day.

9. The method of one of claims 1 or 4, wherein said user does not use therapeutic insulin.

10. The method of claim 1, further comprising:

administering a plurality of insulin boluses within a pre-determined time interval;

calculating a median time for said plurality of insulin boluses;

performing a glucose measurement during said pre-determined time interval and before said median time; and

flagging said glucose measurement as pre-meal if said median time minus a glucose measurement time is greater than a threshold time interval.

12. The method of one of claims 10 or 11, further comprising,

calculating a standard deviation time for said median time;

and

calculating said threshold time interval based on said standard deviation time.

13. The method of one of claims 10 or 11, wherein said threshold time interval is about one hour.

14. The method of one of claims 1 or 3, further comprising:

determining (a) a median of glucose concentration values during a temporal period and (b) a median of test times during the temporal period; and

correlating (a) the median of glucose concentration values and (b) the median of test times to define a data point on a two-dimensional coordinate graph having glucose values and test times.

15. The method of claim 14, further comprising:

determining (i) a median of insulin injection quantities injected by the patient during the temporal period and (ii) a median of injection times during the temporal period; and

correlating (i) the median of insulin injection quantities and (ii) the median of injection incidences to define a data point on a two-dimensional coordinate graph having insulin injection quantities and injection times.

16. The method of claim 15, wherein the temporal period comprises at least one of a specific time period during a day, a plurality of time periods in a day, a specified day in a week, or a plurality of specified days in a week.

17. The method of claim 16, wherein the temporal period comprises at least one of testing incidence having pre-meal tests in a specific time period during a day, testing incidence having pre-meal tests in a specified day of a week, testing incidence having pre-meal tests in a plurality of days in a week, testing incidence having post-meal tests in a specific time period during a day, testing incidence having post-meal tests in a specified day of a week, or testing incidence having post-meal tests in a plurality of days in a week.

2. The method of claim 2, in which the indicating comprise flagging said glucose concentration with a post-meal flag if said glucose concentration measurement during said second time slot is greater than said median glucose concentration by a pre-determined threshold.

4. A method of determining pre-meal time intervals for a diabetes patient, the method comprising:

obtaining a plurality of blood glucose concentration measurements;

calculating a median glucose concentration for blood glucose concentration measurements performed during a second time slot;

performing a glucose concentration measurement during a first time slot, said second time slot is subsequent to said first time slot;

indicating that said glucose concentration tested during said first time slot may be flagged as pre-meal if said glucose concentration measurement during said first time slot is less than said median glucose concentration by a pre-determined threshold.

5. The method of claim 4, wherein said user is provided the option of flagging said glucose concentration with a pre-meal flag if said glucose concentration measurement during said second time slot is less than said median glucose concentration by a pre-determined threshold.

6. The method of claim 5, wherein said pre-determined threshold is about 50 milligrams per deciliter.

11. The method of claim 4, further comprising:

administering a plurality of insulin boluses within a pre-determined time interval;

calculating a median time for said plurality of insulin boluses;

performing a glucose measurement during said pre-determined time interval and after said median time; and

flagging said glucose measurement as post-meal if a glucose measurement time minus said median time is greater than a threshold time interval.