WEEPING BALLOON CATHETER
First Claim
1. A multiple-balloon intraluminal fluid delivery catheter for delivering a fluid into a body vessel comprising:
- a catheter shaft extending along a longitudinal axis from a proximal end to a distal end, the catheter shaft including an inflation lumen to deliver an inflation fluid and a fluid delivery lumen to deliver said fluid;
an inner balloon including a middle region having a first end and a second end, the inner balloon mounted on the distal end of the catheter shaft and in communication with the inflation lumen, the inner balloon being movable between a deflated configuration and an inflated configuration; and
an outer balloon mounted around at least a portion of the inner balloon, the outer balloon having a proximal end and a distal end and a middle portion therebetween, the outer balloon being movable between a compressed configuration and an expanded configuration, the outer balloon including a plurality of holes,the inner balloon and the outer balloon being configured and oriented such that an annular lumen is defined when the inner balloon is in the inflated configuration and the outer balloon is in the expanded configuration, the annular lumen being in communication with the fluid delivery lumen and the plurality of holes,the annular lumen being configured to promote the delivery of said fluid through the plurality of holes, wherein the annular lumen has a portion disposed between the middle region of the inner balloon and the middle portion of the outer balloon, the annular lumen portion having an increasingly smaller cross-sectional area along the longitudinal axis in a distal direction.
3 Assignments
0 Petitions
Accused Products
Abstract
Multiple-balloon catheters, and methods of treatment therewith, are provided including an inflatable inner balloon at least partially enclosed by an expandable outer balloon that has holes. The annular space between the inner balloon and the outer balloon is configured to promote delivery of the fluid evenly through holes in the outer balloon to avoid problems of underloading and/or overloading. Preferably, the annular space is in communication with the holes, and the annular space is configured to receive and then to release and distribute the fluid via the holes in a substantially uniform manner such that even amounts of fluid are released in the distal and proximal holes. The inner balloon may have various configurations including being tapered relative to the outer balloon. The outer balloon may also be tapered accordingly. The device may also include raised portions disposed in the annular space and configured to define channels having various configurations.
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Citations
20 Claims
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1. A multiple-balloon intraluminal fluid delivery catheter for delivering a fluid into a body vessel comprising:
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a catheter shaft extending along a longitudinal axis from a proximal end to a distal end, the catheter shaft including an inflation lumen to deliver an inflation fluid and a fluid delivery lumen to deliver said fluid; an inner balloon including a middle region having a first end and a second end, the inner balloon mounted on the distal end of the catheter shaft and in communication with the inflation lumen, the inner balloon being movable between a deflated configuration and an inflated configuration; and an outer balloon mounted around at least a portion of the inner balloon, the outer balloon having a proximal end and a distal end and a middle portion therebetween, the outer balloon being movable between a compressed configuration and an expanded configuration, the outer balloon including a plurality of holes, the inner balloon and the outer balloon being configured and oriented such that an annular lumen is defined when the inner balloon is in the inflated configuration and the outer balloon is in the expanded configuration, the annular lumen being in communication with the fluid delivery lumen and the plurality of holes, the annular lumen being configured to promote the delivery of said fluid through the plurality of holes, wherein the annular lumen has a portion disposed between the middle region of the inner balloon and the middle portion of the outer balloon, the annular lumen portion having an increasingly smaller cross-sectional area along the longitudinal axis in a distal direction. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A multiple-balloon intraluminal fluid delivery catheter for delivering a fluid into the body vessel comprising:
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a catheter shaft extending along a longitudinal axis from a proximal end to a distal end, the catheter shaft including an inflation lumen to deliver an inflation fluid and a fluid delivery lumen to deliver said fluid; an inner balloon including a middle region having a first end and a second end, the inner balloon mounted on the distal end of the catheter shaft and in communication with the inflation lumen, the inner balloon being movable between a deflated configuration and an inflated configuration, where in the inflated configuration the middle region of the inner balloon has an increasingly larger cross-sectional area; and an outer balloon mounted around the inner balloon, the outer balloon having a proximal end and a distal end and a middle portion therebetween, the outer balloon being movable between a compressed configuration and an expanded configuration, where in the expanded configuration the middle portion has a cross-sectional area sized to contact said body vessel, the outer balloon including a plurality of holes, the inner balloon and the outer balloon being configured and oriented such that an annular lumen is defined when the inner balloon is in the inflated configuration and the outer balloon is in the expanded configuration, where the inner balloon and the outer balloon are independently movable to the inflated configuration and the expanded configuration, respectively, the annular lumen being in communication with the fluid delivery lumen and the plurality of holes, the annular lumen being configured to promote delivery of said fluid evenly through the plurality of holes.
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20. A method of delivering a therapeutic agent to a point of treatment within a body vessel comprising:
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inserting into said body vessel a multiple-balloon catheter over a wire guide, the multiple-balloon catheter including a catheter shaft including an inflation lumen, a fluid delivery lumen, and a wire guide lumen, a deflated inner balloon including a middle region having a first end and a second end, the inner balloon mounted on the catheter shaft and in communication with the inflation lumen, and a compressed outer balloon mounted around at least a portion of the inner balloon, the outer balloon having a proximal end and a distal end and a middle portion therebetween, the outer balloon including a plurality of holes, the inner balloon and the outer balloon being configured and oriented such that an annular lumen is defined when the inner balloon is in an inflated configuration and the outer balloon is in an expanded configuration, the annular lumen being in communication with the fluid delivery lumen and the plurality of holes, the annular lumen being configured to promote the delivery of said therapeutic agent through the plurality of holes, wherein the annular lumen has a portion disposed between the middle region of the inner balloon and the middle portion of the outer balloon, the annular lumen portion having an increasingly smaller cross-sectional area along the longitudinal axis in a distal direction; translating the multiple-balloon catheter through said body vessel to said point of treatment over the wire guide slidably extending through the wire guide lumen; inflating the inner balloon to the inflated configuration to place the outer balloon in contact with a wall of said body vessel; and introducing said therapeutic agent through the fluid delivery lumen at a pressure effective to deliver said therapeutic agent to said body vessel wall through the plurality of holes of the outer balloon.
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Specification