CONTROL SYSTEM AND APPARATUS FOR USE WITH ULTRA-FAST LASER
First Claim
1. A laser system comprising:
- a laser operably emitting a laser beam pulse;
a pulse shaper operably varying a characteristic of the pulse; and
a microscope operably receiving the shaped pulse;
wherein the shaper assists in creating multiphoton intrapulse interference in the pulse to control multiphoton excitation.
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Accused Products
Abstract
A control system and apparatus for use with an ultra-fast laser is provided. In another aspect of the present invention, the apparatus includes a laser, pulse shaper, detection device and control system. A multiphoton intrapulse interference method is used to characterize the spectral phase of laser pulses and to compensate any distortions in an additional aspect of the present invention. In another aspect of the present invention, a system employs multiphoton intrapulse interference phase scan. Furthermore, another aspect of the present invention locates a pulse shaper and/or MIIPS unit between a laser oscillator and an output of a laser amplifier.
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Citations
72 Claims
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1. A laser system comprising:
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a laser operably emitting a laser beam pulse; a pulse shaper operably varying a characteristic of the pulse; and a microscope operably receiving the shaped pulse; wherein the shaper assists in creating multiphoton intrapulse interference in the pulse to control multiphoton excitation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A laser system comprising:
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a coherent light source operably producing laser beam pulses each having a duration less than 51 femtoseconds; a microscope receiving the pulses; optics acting upon the pulses; a pulse shaper shaping and adaptively correcting essentially all orders of spectral phase dispersion introduced by the optics and microscope; and a detector detecting nonlinear optical signals while ignoring the excitation light source. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17)
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18. A laser system comprising:
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at least one laser beam pulse; a pulse shaper shaping and controlling nonlinear optical processes in the pulse; a microscope acting upon the shaped and controlled pulse; and a programmable controller including programmed instructions operably controlling the shaper in a calculated manner without use of a learning algorithm. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
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29. A laser system comprising:
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laser beam pulses, at least one of the pulses having a duration less than 51 femtoseconds; a microscope including an objective; a programmable controller, the microscope being connected to and operably communicating with the controller; and data indicative of phase distortions in at least one of the pulses, introduced by the microscope objective and laser scanning optics, being stored in a memory database in the controller. - View Dependent Claims (30, 31, 32, 33, 34, 35, 36, 37)
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38. A laser system comprising:
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a laser operably emitting a laser beam pulse; a microscope operably receiving the pulse, the microscope includes different objectives; a programmable controller; and optics assisting in measuring phase distortions at a focal plane of the objectives and the controller automatically changing a characteristic of the optics if the objectives are changed. - View Dependent Claims (39, 40, 41)
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42. A laser system comprising:
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an oscillator emitting laser beam pulses; a microscope performing nonlinear optical microscopy with the pulses; and a compressor comprising at least one optic which corrects for nonlinear optical dispersion of at least one of the pulses caused by an optical member associated with the microscope. - View Dependent Claims (43, 44, 45, 46, 47, 48, 49, 50, 51)
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52. A laser system comprising:
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a tunable oscillator emitting at least one laser beam pulse; a detector operably detecting distortion in the at least one pulse; a compressor; a programmable controller connected to the oscillator; at least one optic operably changing a characteristic of the at least one pulse in response to a signal from the controller based at least in part on a real-time signal from the detector, the at least one optic being located in or upstream of the compressor; and a microscope operably conducting nonlinear optical microscopy with the at least one pulse. - View Dependent Claims (53, 54, 55, 56, 57, 58, 59)
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60. A laser system comprising:
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a laser emitting pulses; a pulse shaper; a microscope; and a programmable controller selectively causing the shaper to optimize at least one of the emitting source pulses for;
(a) two photon excitation, (b) three photon excitation, (c) second harmonic imaging, (d) third harmonic imaging, and (e) four wave mixing imaging. - View Dependent Claims (61, 62, 63)
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64. A laser system comprising:
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a fiber optic cable; a laser emitting a laser beam pulse; a pulse shaper operably shaping the pulse; and a microscope objective; the pulse being transmitted by the fiber optic cable from the laser. - View Dependent Claims (65, 66, 67)
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68. A method of using a laser for nonlinear optical microscopy, the method comprising:
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(a) emitting at least one laser beam pulse; (b) focusing the at least one pulse with a microscope; (c) detecting undesired distortions in the at least one pulse after or while the microscope is acting upon the at least one pulse; and (d) calculating a correction to compensate for the pulse distortions within 15 seconds or less. - View Dependent Claims (69, 70, 71, 72)
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Specification