REACTOR

• US 20090258412A1
• Filed: 04/13/2009
• Published: 10/15/2009
• Est. Priority Date: 04/15/2008
• Status: Abandoned Application

• Current Assignee: Sony Corporation (Sony Group Corp.)
• Original Assignee: Sony Corporation (Sony Group Corp.)
• Inventors: Anaguchi, Takanori, Moriwaki, Toshiki
• Application Number:
  US12/422,547
• Publication Number:
  US 20090258412A1
• Time in Patent Office: Days
• US Class Current: 435/286.100
• CPC Class Codes: B01L 2200/147 Employing temperature sensors
• CPC Class Codes: B01L 2300/0654 Lenses; Optical fibres
• CPC Class Codes: B01L 2300/0819 Microarrays; Biochips
• CPC Class Codes: B01L 2300/1822 using Peltier elements
• CPC Class Codes: B01L 2300/1827 using resistive heater
• CPC Class Codes: B01L 7/52 with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples amplification or hybridisation processes per se C12Q1/68; controlling sequential reactions for synthesis B01J19/0046
• CPC Class Codes: G05D 23/1935 using sequential control

Abstract

Disclosed herein is a reactor, including, a plurality of reaction regions, a plurality of heating elements, each arranged in each of the reaction regions, and cooling elements that cool other regions than reaction regions which are heated by the heating elements, wherein the heating element including a heater and a temperature detecting element and having a detection section configured to detect temperature from the temperature detecting element and a temperature control section configured to control the heater'"'"'s temperature according to the detected temperature information.

Claims

1. A reactor, comprising:

a plurality of reaction regions, wherein a first subset of the plurality is arranged in a heating portion and a second subset is arranged in a cooling portion;

a plurality of heating elements, each arranged in one of said reaction regions in said heating portion; and

cooling elements to cool said reaction regions in said cooling portion, wherein

each said heating element comprises

a heater,

a temperature detecting element,

detection means for detecting temperature information from said temperature detecting element, and

temperature control means for controlling a temperature of said heater according to the detected temperature information,

said temperature control means performing

processing for a temperature cycle that includes a first temperature holding control for a denature treatment,

processing for a second temperature holding control to cool from the denature treatment to an annealing treatment and also for the annealing treatment,

processing for a first temperature rise control for a first heating from the annealing treatment to an extension treatment,

processing for a third temperature holding control for the extension treatment, and

processing for a second temperature rise control for a second heating from the extension treatment to the denature treatment.

3. The reactor as defined in claim 1, wherein said processing performed by the temperature control means further includes:

detecting temperature from said temperature detecting element;

calculating an amount of heater control;

controlling said heater; and

controlling said cooling element.

5. The reactor as defined in claim 1, wherein said processing performed by the temperature control means further includes:

detecting temperature from said temperature detecting element;

controlling current to be applied to said temperature detecting element; and

converting a voltage of said temperature detecting element by means of an analog-digital converter.

2. A reactor, comprising:

a plurality of reaction regions, wherein a first subset of the plurality is arranged in a heating portion and a second subset is arranged in a cooling portion;

a plurality of heating elements, each arranged in one of said reaction regions in said heating portion; and

cooling elements to cool said reaction regions in said cooling portion, wherein

each said heating element comprises

a heater,

a temperature detecting element,

detection means for detecting temperature information from said temperature detecting element, and

temperature control means for controlling a temperature of said heater according to the detected temperature information,

said temperature control means performs processing including

a first temperature holding control for a denature treatment,

a temperature down control to cool from the denature treatment to an annealing treatment,

a second temperature holding control for the annealing treatment and an extension treatment, and

a temperature rise control to heat from the extension treatment to the denature treatment.

4. The reactor as defined in claim 2, wherein said processing performed by the temperature control means further includes:

detecting temperature from said temperature detecting element;

calculating an amount of heater control;

controlling said heater; and

controlling the cooling element.

6. The reactor as defined in claim 2, wherein said processing performed by the temperature control means further includes:

detecting temperature from said temperature detecting element;

controlling current to be applied to said temperature detecting element; and

converting a voltage of said temperature detecting element by means of an analog-digital converter.