Methods and systems associated with delivery of one or more agents to an individual

• US 20090259215A1
• Filed: 04/09/2008
• Published: 10/15/2009
• Est. Priority Date: 04/09/2008
• Status: Abandoned Application

• Current Assignee: Gearbox LLC (Intellectual Ventures LLC)
• Original Assignee: Searete LLC (Intellectual Ventures LLC)
• Inventors: Ishikawa, Muriel Y., Wood, Lowell L. JR., Hyde, Roderick A.
• Application Number:
  US12/082,402
• Publication Number:
  US 20090259215A1
• Time in Patent Office: Days
• US Class Current: 604/891.100
• CPC Class Codes: A61B 2560/0214 of power generation or supply
• CPC Class Codes: A61B 2560/0219 of externally powered implanted units
• CPC Class Codes: A61B 5/0017 transmitting optical signals transmission by light H04B10/00
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/68 Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient

Abstract

The present disclosure relates to methods and systems for administration of one or more agents.

Claims

1. A method comprising:

receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual; and

administering one or more agents to the individual with one or more implanted agent delivery devices in response to the one or more signals.

2. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals directly from the one or more sensors.

3. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals from one or more implanted relay devices.

6. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals that include one or more acoustic signals.

12. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals substantially continuously from the one or more sensors.

13. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals from the one or more sensors that are configured to present one or more detectors at different times.

14. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals from the one or more sensors that are configured to present one or more detectors at different times through use of a sacrificial layer.

15. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals from the one or more sensors that are configured to present one or more detectors at different times through use of one or more shape memory polymers.

17. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals from the one or more sensors in response to one or more queries.

18. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals that include information related to one or more concentrations of the one or more agents within the individual.

21. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals that include information related to one or more concentrations of nitric oxide within the individual.

22. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals that include information related to one or more agents that include one or more pharmaceutical agents.

26. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals that include information related to one or more agents that include one or more hormones.

28. The method of claim 1, wherein the receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

receiving the one or more signals that include information related to one or more agents that include one or more cytokines.

30. The method of claim 1, wherein the administering one or more agents to the individual with one or more implanted agent delivery devices in response to the one or more signals comprises:

maintaining the one or more agents substantially within one or more concentration ranges within the individual.

31. The method of claim 1, wherein the administering one or more agents to the individual with one or more implanted agent delivery devices in response to the one or more signals comprises:

maintaining the one or more agents substantially at one or more setpoints within the individual.

32. The method of claim 1, wherein the administering one or more agents to the individual with one or more implanted agent delivery devices in response to the one or more signals comprises:

administering one or more pharmaceutical agents.

36. The method of claim 1, wherein the administering one or more agents to the individual with one or more implanted agent delivery devices in response to the one or more signals comprises:

administering one or more hormones.

38. The method of claim 1, wherein the administering one or more agents to the individual with one or more implanted agent delivery devices in response to the one or more signals comprises:

administering one or more cytokines.

40. The method of claim 1, wherein the administering one or more agents to the individual with one or more implanted agent delivery devices in response to the one or more signals comprises:

administering one or more nitric oxide donors to the individual.

44. The method of claim 1, wherein the administering one or more agents to the individual with one or more implanted agent delivery devices in response to the one or more signals comprises:

administering the one or more agents with one or more motorized agent delivery devices.

45. The method of claim 1, wherein the administering one or more agents to the individual with one or more implanted agent delivery devices in response to the one or more signals comprises:

administering the one or more agents with one or more charge activated agent delivery devices.

46. The method of claim 1, wherein the administering one or more agents to the individual with one or more implanted agent delivery devices in response to the one or more signals comprises:

transmitting the one or more signals in response to administration of the one or more agents to the individual.

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89. A system comprising:

means for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual; and

means for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the means for receiving the one or more signals.

90-93. -93. (canceled)

94. A method comprising:

receiving one or more acoustic signals that include information related to one or more agents from one or more sensors that are implanted within an individual; and

administering one or more agents to the individual with one or more implanted agent delivery devices that maintain the one or more agents substantially at one or more setpoints within the individual in response to the one or more acoustic signals.