Methods and systems associated with delivery of one or more agents to an individual

• US 20090259217A1
• Filed: 06/05/2008
• Published: 10/15/2009
• Est. Priority Date: 04/09/2008
• Status: Abandoned Application

• Current Assignee: Searete LLC (Intellectual Ventures LLC)
• Original Assignee: Searete LLC (Intellectual Ventures LLC)
• Inventors: Ishikawa, Muriel Y., Wood, Lowell L. JR., Hyde, Roderick A.
• Application Number:
  US12/157,159
• Publication Number:
  US 20090259217A1
• Time in Patent Office: Days
• US Class Current: 604/891.100
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

The present disclosure relates to methods and systems for administration of one or more agents.

Claims

1-46. -46. (canceled)

47. A system comprising:

circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual; and

circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals.

48. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals directly from the one or more sensors.

49. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals from one or more implanted relay devices.

50. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include one or more ultrasonic signals.

51. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include one or more infrared signals.

52. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include one or more acoustic signals.

53. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include one or more optical signals.

54. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include one or more electromagnetic signals.

55. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include one or more microwave signals.

56. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include one or more radio signals.

57. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include one or more radio frequency signals.

58. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals substantially continuously from the one or more sensors

59. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals from the one or more sensors that are configured to present one or more detectors at different times.

60. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals from the one or more sensors that are configured to present one or more detectors at different times through use of a sacrificial layer.

61. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals from the one or more sensors that are configured to present one or more detectors at different times through use of one or more shape memory polymers.

62. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals from the one or more sensors according to one or more time schedules.

63. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals from the one or more sensors in response to one or more queries.

64. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include information related to one or more concentrations of the one or more agents within the individual.

65. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include information related to one or more concentrations of one or more metabolites of the one or more agents within the individual.

67. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include information related to one or more concentrations of nitric oxide within the individual.

68. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include information related to one or more agents that include one or more pharmaceutical agents.

70. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include information related to one or more agents that include one or more hormones.

72. The system of claim 47, wherein the circuitry for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual comprises:

circuitry for receiving the one or more signals that include information related to one or more agents that include one or more cytokines.

74. The system of claim 47, wherein the circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals comprises:

circuitry for maintaining the one or more agents substantially within one or more concentration ranges within the individual.

75. The system of claim 47, wherein the circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals comprises:

circuitry for maintaining the one or more agents substantially at one or more setpoints within the individual.

76. The system of claim 47, wherein the circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals comprises:

circuitry for administering one or more pharmaceutical agents.

78. The system of claim 47, wherein the circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals comprises:

circuitry for administering one or more hormones.

80. The system of claim 47, wherein the circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals comprises:

circuitry for administering one or more cytokines.

82. The system of claim 47, wherein the circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals comprises:

circuitry for administering one or more nitric oxide donors to the individual.

83. The system of claim 47, wherein the circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals comprises:

circuitry for administering one or more photolyzable nitric oxide donors to the individual.

84. The system of claim 47, wherein the circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals comprises:

circuitry for administering one or more nitric oxide donors to the individual that include one or more diazeniumdiolates, trans-[RuCl([15]aneN4)NO]+2, nitrosyl ligands, 6-Nitrobenzo[a]pyrene, S-nitroso-glutathione, S-nitrosothiols, 2-Methyl-2-nitrosopropane, nitroglycerine, L-arginine, or imidazolyl derivatives.

85. The system of claim 47, wherein the circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals comprises:

circuitry for administering the one or more agents with one or more osmotic agent delivery devices.

86. The system of claim 47, wherein the circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals comprises:

circuitry for administering the one or more agents with one or more motorized agent delivery devices.

87. The system of claim 47, wherein the circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals comprises:

circuitry for administering the one or more agents with one or more charge activated agent delivery devices.

88. The system of claim 47, wherein the circuitry for administering one or more agents to the individual with one or more agent delivery devices that are implanted within the individual and responsive to the circuitry for receiving the one or more signals comprises:

circuitry for transmitting the one or more signals in response to administration of the one or more agents to the individual.

66. (canceled)

69. (canceled)

71. (canceled)

73. (canceled)

77. (canceled)

79. (canceled)

81. (canceled)

89. (canceled)

90. A system comprising:

a signal-bearing medium bearing;

one or more instructions for receiving one or more signals that include information related to one or more agents from one or more sensors that are implanted within an individual; and

one or more instructions for administering one or more agents to the individual with one or more implanted agent delivery devices in response to the one or more signals.

91. The system of claim 90, wherein the signal-bearing medium includes a computer-readable medium.

92. The system of claim 90, wherein the signal-bearing medium includes a recordable medium.

93. The system of claim 90, wherein the signal-bearing medium includes a communications medium.

94. A system comprising:

circuitry for receiving one or more acoustic signals that include information related to one or more agents from one or more sensors that are implanted within an individual; and

circuitry for administering one or more agents to the individual with one or more implanted agent delivery devices that maintain the one or more agents substantially at one or more setpoints within the individual in response to the circuitry for receiving one or more acoustic signals.