SENSOR FOR PERCUTANEOUS INTRAVASCULAR DEPLOYMENT WITHOUT AN INDWELLING CANNULA
First Claim
Patent Images
1. A kit for introducing an analyte sensor into a blood vessel, comprising:
- the analyte sensor comprising a distal end region, a proximal end region, and an elongate body, wherein the analyte sensor is sized and configured for percutaneous insertion into the blood vessel, and wherein the analyte sensor comprises an indicator system immobilized along the distal end region, said indicator system being adapted to generate a signal related to the concentration of analyte in the blood, wherein the indicator system is operably coupled to the proximal end region; and
a removable introducer having a distal end region, a proximal end region, and an elongate body comprising a lumen configured to slidably receive the analyte sensor, wherein the elongate body of the introducer has at least one score line along a longitudinal axis, wherein the score line is a weakened portion of the elongate body.
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention relates to a sensor for percutaneous insertion and intravascular residence without an indwelling cannula. In preferred embodiments, a glucose sensor is inserted into a blood vessel using a removable cannula. After the cannula is removed, the glucose sensor remains within the blood vessel by itself and forms a seal with the patient'"'"'s tissue.
-
Citations
36 Claims
-
1. A kit for introducing an analyte sensor into a blood vessel, comprising:
-
the analyte sensor comprising a distal end region, a proximal end region, and an elongate body, wherein the analyte sensor is sized and configured for percutaneous insertion into the blood vessel, and wherein the analyte sensor comprises an indicator system immobilized along the distal end region, said indicator system being adapted to generate a signal related to the concentration of analyte in the blood, wherein the indicator system is operably coupled to the proximal end region; and a removable introducer having a distal end region, a proximal end region, and an elongate body comprising a lumen configured to slidably receive the analyte sensor, wherein the elongate body of the introducer has at least one score line along a longitudinal axis, wherein the score line is a weakened portion of the elongate body. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
-
-
16. A method for deploying a sensor in a blood vessel of a patient, comprising:
positioning the sensor in the blood vessel, such that at least a distal portion of the sensor resides within the blood vessel and at least a proximal portion of the sensor extends out of the patient, wherein there are no additional components associated with the sensor within the patient. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25)
-
26. A method for measuring an analyte concentration in a blood vessel, comprising:
-
providing a sensor configured to reside at least in part within the blood vessel and generate a signal related to the analyte concentration in the blood; introducing the sensor into the blood vessel through an introducer assembly; removing the introducer assembly, leaving only the analyte sensor in the patient; and detecting the signal to measure the analyte concentration in the blood. - View Dependent Claims (27, 28)
-
-
29. A method for deploying a sensor in a blood vessel, comprising:
-
providing an introducer assembly comprising a hypodermic needle slidably engaged within a splitable cannula, wherein a piercing tip of the hypodermic needle extends distally beyond the splitable cannula; cannulating the blood vessel with the introducer assembly; withdrawing the hypodermic needle while leaving the splitable cannula in the blood vessel; inserting the sensor through the splitable cannula and into the blood vessel; withdrawing the splitable cannula from the blood vessel while leaving the sensor in the blood vessel; and splitting and removing the cannula from the sensor. - View Dependent Claims (30, 31, 32, 33, 34, 35)
-
-
36. A method for continuous monitoring of blood glucose levels in a patient, comprising:
-
providing an introducer assembly comprising a hypodermic needle slidably engaged within a removable cannula, wherein a piercing tip of the hypodermic needle extends distally beyond the removable cannula; inserting the introducer assembly into a peripheral vein or artery; retracting the hypodermic needle from the removable cannula, while leaving the removable cannula in the peripheral vein or artery; providing an optical glucose sensor comprising a fluorescent indicator system disposed along a distal end region and adapted to generate an optical signal related to the blood glucose level in response to light, an elongate fiber-optic body, and an optical coupling disposed along a proximal end region; inserting the optical glucose sensor through the removable cannula and into the peripheral vein or artery; retracting the removable cannula from the vein or artery, while leaving the sensor in the peripheral vein or artery; removing the removable cannula from the sensor; connecting the optical coupling to a device comprising a light source and a detector; and detecting the optical signal to monitor the blood glucose level of the patient.
-
Specification