METHOD OF AND SYSTEM FOR SIGNAL SEPARATION DURING MULTIVARIATE PHYSIOLOGICAL MONITORING
First Claim
1. :
- A method of outputting an indication of the timing and morphology of a monitored signal from at least a part of a biological organ comprising the steps of;
acquiring a multivariate signal via a plurality of sensors as observations, including a desired signal attributable to at least a part of a biological organ signal source and one or more superimposed other signals where at least one pair of the signals from the multivariate signal exhibits partial correlation;
extracting the desired signal from the acquired physiologic signal, wherein the desired signal is a periodically recurring set of features of interest not limited to independent components from the observations;
monitoring the timing of an occurrence and reoccurrences of at least one of the features of interest; and
generating an output signal relative to the time period between the occurrence and the reoccurrences of the at least one of the features of interest.
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Accused Products
Abstract
Multiple electrode contacts make electrical connections to the anterior and/or posterior chest for multivariate characterization of the electrical activation of the heart. A central processing unit derives synthetic composite electrographic signals as well as flag signals for specific purposes. A preferred embodiment uses this system to trigger or gate magnetic resonance imaging, eliminating or reducing problems from small or inverted R-waves, lead detachment, noise, flow signal, gradient changes, and rhythm changes, more reliably flagging the onset of electrical activation of the ventricles. Additional derived data are ST-segment shifts, filling times, and respiratory cycle. Filling times may be used for greatly improved imaging in the presence of rhythm disturbances, such as atrial fibrillation. Respiratory cycle may be used as a respiratory trigger to control for the effects of breathing on the heart position and image quality.
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Citations
20 Claims
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1. :
- A method of outputting an indication of the timing and morphology of a monitored signal from at least a part of a biological organ comprising the steps of;
acquiring a multivariate signal via a plurality of sensors as observations, including a desired signal attributable to at least a part of a biological organ signal source and one or more superimposed other signals where at least one pair of the signals from the multivariate signal exhibits partial correlation; extracting the desired signal from the acquired physiologic signal, wherein the desired signal is a periodically recurring set of features of interest not limited to independent components from the observations; monitoring the timing of an occurrence and reoccurrences of at least one of the features of interest; and generating an output signal relative to the time period between the occurrence and the reoccurrences of the at least one of the features of interest. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 18, 20)
- A method of outputting an indication of the timing and morphology of a monitored signal from at least a part of a biological organ comprising the steps of;
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10. :
- A system of outputting an indication of at least one of the timing and morphology of a monitored physiologic signal produced by at least a part of a biological organ, comprising the steps of;
a plurality of sensors adapted to be located at different positions relative to the at least a part of a biological organ for acquiring a multivariate signal via the plurality of sensors, including a desired signal attributable to at least a part of a biological organ signal and one or more superimposed contaminant signals, wherein at least one pair of the signals from the multivariate physiologic signal exhibits partial correlation; a data processor in data communication with the plurality of sensors and executing the steps of; extracting the desired signal from the acquired physiologic signal, wherein the desired signal is comprised of a periodically recurring set of features of interest; monitoring occurrences of at least one of the features of interest; and outputting an indicator of at least one of the features of interest and variations thereof. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 19)
- A system of outputting an indication of at least one of the timing and morphology of a monitored physiologic signal produced by at least a part of a biological organ, comprising the steps of;
Specification