MEDICAL DEVICES HAVING DURABLE AND LUBRICIOUS POLYMERIC COATING

• US 20090264912A1
• Filed: 04/15/2008
• Published: 10/22/2009
• Est. Priority Date: 10/03/2000
• Status: Abandoned Application

• Current Assignee: Dennis D. Jamiolkowski, Jesse G. Nawrocki
• Original Assignee: Dennis D. Jamiolkowski, Jesse G. Nawrocki
• Inventors: Nawrocki, Jesse G., Jamiolkowski, Dennis D.
• Application Number:
  US12/103,341
• Publication Number:
  US 20090264912A1
• Time in Patent Office: Days
• US Class Current: 606/185
• CPC Class Codes: A61L 2420/02 Methods for coating medical devices
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: C08L 83/04 Polysiloxanes

Abstract

A medical device having a contact surface exposed repeatedly to bodily tissue is disclosed. The contact surface is coated with a silicone polymer and one or more non-silicone hydrophobic polymers. The preferred medical device is a surgical needle, and the preferred coating is a polydimethylsiloxane and polypropylene wax hydrocarbon mixture. The incorporation of the non-silicone hydrophobic polymer increases the durability of the coating on the device without sacrificing lubricity.

Claims

1-17. -17. (canceled)

18. :

A process for coating a contact surface of a medical device exposed repeatedly to bodily tissue, the process comprising the steps of;

a) applying a first layer of a non-silicone hydrophobic polymer to the contact surface; and

,

b) applying a second layer of a silicone polymer over the first layer.

19. :

The process for coating as set forth in claim 18 wherein the silicone polymer is a polyalkylsiloxane.

20. :

The process for coating as set forth in claim 19 wherein the polyalkylsiloxane is a polydimethylsiloxane.

21. :

The process for coating as set forth in claim 20 wherein the non-silicone hydrophobic polymer has a critical surface tension of less than about 50 mN/m.

22. :

The process for coating as set forth in claim 21 wherein the non-silicone hydrophobic polymer is a thermoplastic polymer.

23. :

The process for coating as set forth in claim 22 wherein the thermoplastic polymer is flowable at less than about 210°

C.

24. :

The process for coating as set forth in claim 18 wherein the second layer comprises about 50 to about 100 weight percent of polydimethylsiloxane and the first layer comprises about 50 to about 100 weight percent of a thermoplastic polymer.

25. :

The process for coating as set forth in claim 24 wherein the medical device is a surgical needle.

26. :

The process for coating as set forth in claim 25 wherein the polydimethylsiloxane is hydroxy terminated.

27. :

The process for coating as set forth in claim 26 wherein the thermoplastic polymer is polyethylene, polypropylene or polycaprolactone.

42. :

The process of claim 25, wherein the medical device comprises at least one piercing point.

44. :

The process of claim 25, wherein the medical device comprises at least one cutting edge.

45. :

The process of claim 25, wherein the medical device comprises a tissue penetrating portion.

28. :

A coated medical device, comprising;

a medical device having a surface;

a first coating applied to at least a portion of the surface, said coating comprising a non-silicone hydrophobic polymer; and

,

a second coating applied over the first coating, said second coating comprising a silicone polymer.

29. :

The medical device of claim 28 wherein the silicone polymer is a polysiloxane.

30. :

The medical device of claim 29 wherein the polysiloxane is a polyalkylsiloxane.

31. :

The medical device of claim 30 wherein the polyalkylsiloxane is a polydimethylsiloxane.

32. :

The medical device of claim 28 wherein the non-silicone hydrophobic polymer has a critical surface tension of less than about 50 mN/m.

33. :

The medical device of claim 28 wherein the non-silicone hydrophobic polymer is a thermoplastic polymer.

34. :

The medical device of claim 33 wherein the thermoplastic polymer is flowable at less than about 210°

C.

35. :

The medical device of claim 28 wherein the second coating comprises about 50 to about 100 weight percent of polydimethylsiloxane and the first coating comprises about 150 to about 100 weight percent of a thermoplastic polymer.

36. :

The medical device of claim 28 wherein the second coating comprises about 50 to about 100 weight percent of polydimethylsiloxane and the first coating comprises about 50 to about 100 weight percent of a thermoplastic polymer selected from the group consisting of polyethylene, polypropylene, and polycaprolactone.

37. :

The medical device of claim 28 wherein the medical device is a surgical needle.

38. :

The medical device of claim 31 wherein the polydimethylsiloxane is hydroxy terminated.

39. :

The medical device of claim 33 wherein the thermoplastic polymer is selected from the group consisting of polyethylene, polypropylene and polycaprolactone.

40. :

The medical device of claim 28 wherein the second coating comprises a hydroxy terminated polydimethylsiloxane and the first coating comprises a non-silicone hydrophobic polymer selected from the group consisting of polyethylene, polypropylene and polycaprolactone.

41. :

The medical device of claim 28, wherein the medical device comprises at least one cutting edge.

43. :

The medical device of claim 28, wherein the medical device comprises at least one piercing point.

46. :

the medical device of claim 28, wherein the medial device comprises a tissue penetrating portion

47. :

A process for coating a contact surface of a medical device exposed repeatedly to bodily tissue, the process comprising the steps of

a) mixing a silicone polymer and a non-silicone hydrophobic polymer with a solvent to form a coating mixture,

b) applying the coating mixture to the contact surface, and

c) removing the solvent from the coating mixture.

48. :

The process for coating as set forth in claim 47, wherein the silicone polymer is soluble in the solvent.

49. :

The process for coating as set forth in claim 48 wherein the silicone polymer is a polyalkylsiloxane.

50. :

The process for coating as set forth in claim 49 wherein the polyalkylsiloxane is a polydimethylsiloxane.

51. :

The process for coating as set forth in claim 50 wherein the non-silicone hydrophobic polymer has a critical surface tension of less than about 50 mN/m.

52. :

The process for coating as set forth in claim 51 wherein the non-silicone hydrophobic polymer is a thermoplastic polymer.

53. :

The process for coating as set forth in claim 52 wherein the thermoplastic polymer is flowable at less than about 210°

C.

54. :

The process for coating as set forth in claim 50 wherein the coating has about 44 to about 66 weight percent of the polydimethylsiloxane and about 34 to about 56 weight percent of the thermoplastic polymer.

55. :

The process for coating as set forth in claim 54 wherein the medical device is a surgical needle.

56. :

The process for coating as set forth in claim 55 wherein the polydimethylsiloxane is hydroxy terminated.

57. :

The process for coating as set forth in claim 56 wherein the thermoplastic polymer is polyethylene, polypropylene or polycaprolactone