Concentrated Liquid Thyroid Hormone Composition
First Claim
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1. A liquid pharmaceutical composition, wherein:
- the composition comprises;
at least one thyroid hormone,hydroxypropyl-β
-cyclodextrin,at least one buffer, andat least 5% (by weight) water; and
the pH of the composition is from about 8 to about 12.
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Abstract
This invention is directed generally to a liquid pharmaceutical composition comprising at least one thyroid hormone (particularly a composition further comprising at least one cyclodextrin compound), a process for making such a composition and a method of using such a composition to treat a condition associated with impaired thyroid hormone function.
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Citations
21 Claims
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1. A liquid pharmaceutical composition, wherein:
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the composition comprises; at least one thyroid hormone, hydroxypropyl-β
-cyclodextrin,at least one buffer, and at least 5% (by weight) water; and the pH of the composition is from about 8 to about 12. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 16, 17, 18)
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14. A liquid pharmaceutical composition, wherein the composition comprises:
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at least one thyroid hormone, greater than 1% (by weight) hydroxypropyl-α
-cyclodextrin,at least one buffer, and at least 5% (by weight) water. - View Dependent Claims (15, 20, 21)
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19. (canceled)
Specification