STIMULI-RESPONSIVE SURFACES

• US 20090274877A1
• Filed: 03/11/2009
• Published: 11/05/2009
• Est. Priority Date: 03/11/2008
• Status: Abandoned Application

• Current Assignee: Brigham and Women's Hospital Incorporated, Massachusetts Institute of Technology
• Original Assignee: Brigham and Women's Hospital Incorporated
• Inventors: Chan, Edwin, Langer, Robert S., Karp, Jeffrey M.
• Application Number:
  US12/402,154
• Publication Number:
  US 20090274877A1
• Time in Patent Office: Days
• US Class Current: 428/167
• CPC Class Codes: B32B 33/00 Layered products characterised by particular properties or particular surface features, e.g. particular surface coatings; Layered products designed for particular purposes not covered by another single class
• CPC Class Codes: Y10T 156/10 Methods of surface bonding and/or assembly therefor
• CPC Class Codes: Y10T 428/2457 Parallel ribs and/or grooves

Abstract

A material capable of promoting adhesion through transitioning reversibly between a first state and a second state when the material is exposed to or removed from a stimulus, wherein, the first state includes a first texture and the second state includes a second texture different from the first texture.

Claims

1. A material capable of promoting adhesion through transitioning reversibly between a first state and a second state when the material is exposed to or removed from a stimulus,

wherein, the first state comprises a first texture and the second state comprises a second texture different from the first texture.

2. The material of claim 1 wherein, when the stimulus changes the texture returns to the first state.

3. The material of claim 1 wherein the change in stimulus is selected from the group consisting of removal of the stimulus, reduction in the degree of the stimulus, increase in the degree of the stimulus, addition of a second stimulus.

4. The material of claim 1 wherein the material is a polymer.

5. The material of claim 1 wherein, the material locally pins the interface contact from receding.

6. The material of claim 1 wherein, de-adhesion can be promoted by removing the stimulus.

7. The material of claim 1, wherein during the first state the texture has amplitude in the range of between about 250 nm and about 500 nm and wavelength in the range of between about 250 nm and about 500 nm and during the second state the texture has amplitude in the range of between about 250 μ

m and about 500 μ

m and wavelength in the range between of about 250 μ

m and about 500 μ

m.

8. The material of claim 1 wherein the texture has during the first state the texture has amplitude in the range of between about 1 μ

m and about 50 μ

m and wavelength in the range of between about 25 μ

m and about 75 μ

m and during the second state the texture has amplitude in the range of between about 200 μ

m and about 300 μ

m and wavelength in the range between of about 250 μ

m and about 500 μ

m.

9. The material of claim 1 further comprising a substrate or mold.

10. The material of claim 9 further comprising an adhesive between the material and substrate.

11. The material of claim 1 wherein the stimulus is selected from the group consisting of hydration/dehydration, change in solvent, change in pH, change in temperature, change in pressure, exposure to electromagnetic radiation, enzymatic activity, change in ionic strength, application of an electric field, application of a magnetic field, application of mechanical stress and combinations thereof.

12. The material of claim 11 wherein the stimulus is hydration.

13. The material of claim 12 wherein the hydration is from a tissue.

14. The material of claim 4 where in the polymer is selected from the group consisting of poly(ethylene glycol methyl ether acrylate-co-acrylic acid) (“

p(PEGA-AA)”

), poly(glycerol sebacate)(PGS), poly(glycerol sebacate acrylate) (PGSA), poly(lactic-co-glycolic acid) (PLGA), polycaprolactone (PCL), polyglycolide (PGA), polylactic acid (PLA), poly-3-hydroxybutyrate (PHB), polyurethane, parylene-C, keratin, carbon nanotubes, poly(anhydride), chitosan, 2-hydroxyethylmethacrylate, hylauronic acid, poly(acrylic acid), poly(ethylene glycol), copolymers and combinations thereof.

15. The material of claim 4 wherein the polymer is a bilayer of bulk material layer and a top layer.

17. The material of claim 15 wherein the top layer is formed from the monomers of the bulk material during initial polymerization.

18. The material of claim 4 wherein the polymer is cross-linked.

19. The material of claim 1 further comprising a biomolecule or pharmaceutical compound.

21. The material of claim 1 further comprising a plurality of cells.

23. The material of claim 1 wherein the texture has a pattern.

24. The material of claim 1 wherein the texture is in a random arrangement.

25. The material of claim 1 wherein the transition from the first state to the second state results in a change in the range between about 50%, and about 500%.

26. The material of claim 1 in the form of a tape.

27. The material of claim 1 wherein the adhesion against deformable surfaces is greater than adhesion against rigid surfaces.

28. The material of claim 1 wherein the material is contacted to a superstrate.

29. The material of claim 28 wherein the material is adhered to a wet, deformable superstrate.

30. The material of claim 28 where in the material is adhered to a dry, deformable superstrate.

31. The material of claim 28 wherein the material increase the contact line at separation of the material and superstrate due to the transition from one state to the other.

32. The material of claim 31 wherein the contact line is increased by locally pinning the separation pathway due to the transition from one state to the other.

33. The material of claim 28 wherein the material and superstrate can be de-adhered through transitioning from one state to the other.

34. The material of claim 33 wherein the transition decreases the contact line at separation.

35. The material of claim 28 wherein the superstrate prevents complete reversal of the transition from the first state to the second state.

36. The material of claim 1, wherein the adhesive strength is increased as the amplitude of the texture increases.

37. The material of claim 36 wherein the increase in adhesive strength is coincident with increase in contact time with a superstrate.

40. The material of claim 1 further comprising additives.

16. (canceled)

20. (canceled)

22. (canceled)

38-39. -39. (canceled)

41. (canceled)

42. A method comprising

contacting a material with a superstrate, the material comprising

a material capable of promoting adhesion through transitioning reversibly between a first state and a second state when the material is exposed to or removed from a stimulus,

wherein, the first state comprises a first texture and the second state comprises a second texture different from the first texture

43-69. -69. (canceled)

70. A method of making a composition comprising:

photo polymerizing a mixture of polymers and a photoinitiator in a mold or a rigid substrate.

71-72. -72. (canceled)

73. A method of improving adhesion comprising

contacting a stimuli response material with a superstrate

applying a stimulus

wherein the stimulus causes the stimuli responsive material to transition from a first state to a second state

wherein the second state has a more irregular topology relative to the first state.