Flowometry in Optical Coherence Tomography for Analyte Level Estimation
First Claim
19. A method for determining the presence of fluid flow in a tissue sample using optical coherence tomography, comprising:
- scanning a region in the tissue sample using OCT to provide fringe-modulated intensity data measurements; and
using amplitude modulation in the fringe-modulated intensity data measurements to determine whether fluid flow is present in the region.
6 Assignments
0 Petitions
Accused Products
Abstract
Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.
-
Citations
38 Claims
-
19. A method for determining the presence of fluid flow in a tissue sample using optical coherence tomography, comprising:
scanning a region in the tissue sample using OCT to provide fringe-modulated intensity data measurements; and
using amplitude modulation in the fringe-modulated intensity data measurements to determine whether fluid flow is present in the region.
-
20-25. -25. (canceled)
-
26. A system for determining at least one blood characteristic in a tissue sample, comprising:
-
an optical coherency tomography (OCT) apparatus configured to obtain intensity data measurements from each of a plurality of regions in the tissue sample; and a processor configured to analyze the intensity data measurements from the OCT apparatus to determine whether blood flow is present in at least one region. - View Dependent Claims (1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38)
-
-
33-1. The system of claim 26, wherein the processor is configured to analyze fringe-modulated data in the intensity data measurements.
Specification