Temperature-compensated in-vivo sensor
First Claim
1. An in-vivo sensor assembly comprising:
- an assembly body having a body proximal end and a body distal end;
a plurality of sensor elements including at least an analyte sensor element containing an enzyme that is a substrate of the analyte to be measured, a reference sensor element and a temperature sensor element disposed at or near the body distal end wherein the at least an analyte sensor element and the reference sensor element are exposed to the sample fluid and the temperature sensor is capable of measuring the temperature of and adjacent to the analyte sensor element; and
an electrical coupling means disposed at the body proximal end and configured to couple to the at least an analytical sensor element, the reference sensor element and the temperature sensor element.
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Accused Products
Abstract
An in-vivo sensor assembly includes an assembly body having a body proximal end and a body distal end, a plurality of sensor elements including at least an analyte sensor element containing an enzyme that is a substrate of the analyte to be measured, a reference sensor element and a temperature sensor element disposed at or near the body distal end wherein the at least an analyte sensor element and the reference sensor element are exposed to the sample fluid and the temperature sensor is capable of measuring the temperature of and adjacent to the analyte sensor element, and an electrical coupling means disposed at the body proximal end and configured to couple to the at least an analytical sensor element, the reference sensor element and the temperature sensor element.
74 Citations
37 Claims
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1. An in-vivo sensor assembly comprising:
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an assembly body having a body proximal end and a body distal end; a plurality of sensor elements including at least an analyte sensor element containing an enzyme that is a substrate of the analyte to be measured, a reference sensor element and a temperature sensor element disposed at or near the body distal end wherein the at least an analyte sensor element and the reference sensor element are exposed to the sample fluid and the temperature sensor is capable of measuring the temperature of and adjacent to the analyte sensor element; and an electrical coupling means disposed at the body proximal end and configured to couple to the at least an analytical sensor element, the reference sensor element and the temperature sensor element. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. An in-vivo sensor assembly for measuring an analyte in a fluid in a body, the sensor assembly comprising:
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a sheath; a hub having a hub sheath portion and a hub cap connected to the hub sheath portion, the hub sheath portion sealingly connected to a proximal end of the sheath, the hub cap having a connector receiver port; and a sensor shank sealingly disposed within the sheath and having a shank distal end and a shank proximal end, the sensor shank comprising; a plurality of sensor elements including at least an analyte sensor element for generating a signal in response to an analyte concentration in a body, a reference sensor element and a temperature sensor element for determining a temperature of an area adjacent to the analyte sensor element and for compensating for an output of the analyte sensor element, the plurality of sensor elements disposed adjacent the shank distal end and exposed to the fluid of the body; a plurality of contact ears extending substantially parallel to the longitudinal axis of the sensor shank from the shank proximal end, the plurality of contact ears having one or more electrical connector pads wherein the plurality of contact ears are offset from the sensor shank and from each other, the electrical connector pads being electrically coupled to the plurality of sensor elements; and an electrical connector having a shank connector board and an electrical connector receiver coupled to the shank connector board, the shank connector board being received and captured between the plurality of contact ears wherein the connector pads of the plurality of contact ears are electrically coupled to the electrical connector receiver wherein the electrical connector and the shank proximal end are disposed within the hub cap, the connector receiver being aligned with the connector receiver port in the hub. - View Dependent Claims (16, 17, 18)
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19. An in-vivo sensor assembly insertable into a conventional intravenous catheter, the sensor assembly comprising:
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a sheath having a sheath proximal end and a sheath distal end wherein an outer diameter of the sheath is sized to be substantially equal to the outer diameter of an insertion needle of the intravenous catheter; a hub sealingly connected to the sheath proximal end, the hub adapted for removably coupling to the intravenous catheter; a sensor disposed within the sheath, the sensor having a sensor shank with a shank distal end and a shank proximal end, a plurality of sensor elements including at least an analyte sensor element for generating a signal in response to an analyte concentration in a body, a reference sensor element and a temperature sensor element for determining a temperature of an area adjacent to the analyte sensor element and for compensating for an output of the analyte sensor element, the plurality of sensor elements disposed adjacent the shank distal end, a plurality of connector pads disposed at the shank proximal end wherein the plurality of connector pads are contained within the hub, and a plurality of elongated conductive elements wherein each of the plurality of conductive elements electrically couples one of the plurality of sensor elements to one of the plurality of connector pads; and an electrical coupling means for coupling to the plurality of connector pads. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37)
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Specification